Lipopeptidos Flashcards

1
Q

Mecanismo de accion de los lipopeptidos

A

Inhiben la sintesis de peptidoglucano creando poros en la pared celular. Son bactericidas

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2
Q

Via de administracion y excrecion de la daptomicina

A

Se administra VE y se excreta via R

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3
Q

Cobertura de la daptomicina

A
MRSA
LRSA
VRSA
Estreptococo
VRE
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4
Q

Efectos adversos de la daptomicina

A

Miolisis

Elevan CPK

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5
Q

La daptomicina se puede utilizar en el embarazo?

A

Si

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6
Q

La daptomicina atraviesa la BHE?

A

No

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7
Q

Contraindicaciones de la daptomicina

A

Neumonia
Estatinas o fibratos
Fascitis necrosante

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8
Q

Indicaciones de la daptomicina

A

IVU (por VRE)

Infecciones resistentes a vancomicina como: endocarditis, meningitis, osteomielitis, IPBT

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9
Q

Que inactiva a la daptomicina?

A

El surfactante pulmonar

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10
Q

La daptomicina debe estar refrigerada?

A

Si

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