Overview of lymphatics system of the body Flashcards
How much fluid is absorbed by the lymphatic system and why does this happen?
3 litres of fluid and electrolytes in the extracellular spaces fail to be reabsorbed per day so lymphatic system drains the excess into the subclavian veins, using skeletal muscle and respiratory pumps.
Which has more white blood cells plasma or lymph?
Lymph
carriers dietary fats too
Dual and uni flow of lymph?
what side are the nodes
flow in one direction and nodes tend to be on the flexor side
What cells allow one way flow and how?
Endothelial cells overlap to allow one-way flow. Anchoring filaments attach them to tissues, when pressure increases the cells are pulled apart allowing more fluid to enter.
5 lymph trunks
jugular - head and neck
subclavian - upper limbs
bronchomediastinal - ( thoracic, lung and heart)
intestinal - stomach spleen liver and pancreas
lumbar - lower limb and abdominal wall
what the two ducts that drain the body?
Thoracic duct - about 38-45cm starts as a dilation of the cistern chill ( pool) and this receives lymph from lower limbs, lumbar/intetinal trunks and left jug and subclavian and brochomediastinal trunks - its the main repository , everything below belly Button
1/4 drained by the right lymphatic duct 1.2cm long and drains right jug and subclavian and BMS
normally drain Into subclavian or jugular after that
testicular cancer is associated with which node
Para-aortic nodes
chest - embryology , aorta
Gastric cancer is associated with which node
Virchow’s node
Breast cancer is associated with which node
Axillary nodes
primary lymphatic organ
produce/mature lymphocytes - red bone marrow, thymus gland
secondary lymphatic organ
where immune responses occur – lymph nodes, spleen, tonsils, lymph nodules
Thymus and how it changes as you get older
large in infants but atrophies in size after puberty and becomes fat infiltrated in adults and site of T cell development and maturation
Function of the spleen
Functions as blood filter and plays a role in cell-mediated and humoral immune response
Can you normally feel the spleen?
Not normally palpable (if lower edge felt on inspiration- enlarged x3)
Role of white pulp
Important role in normal immune response to infection
Comprises lymph-related nodules (malpighian corpuscules)