Cells of the Blood Flashcards

1
Q

Function of plasma- what does it help maintain

A

helps maintain blood pressure and regulates body temperature

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2
Q

function of RBC

A

transports oxygen and CO2

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3
Q

function of leukocytes

A

Destroys pathogens, produces antibodies against bacteria and viruses, destroy infected and cancerous cells

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4
Q

function of thrombocytes

A

prevent bleeding

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5
Q

Function and appearance of Neutrophil

A

multi lobed nucleus

Bacterial or fungal infection. These are the most common first responders to microbial infection- phagocytosis

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6
Q

Function and appearance of eosinophil

A

bi-lobed

Parasitic infections and allergic reactions (Inflammatory)

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7
Q

Function and appearance of basophil

A

bi/tri lobed nucleus

Allergic and antigen response (releases histamine causing vasodilation)

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8
Q

Function and appearance of lymphocyte

A

deep stained eccentric nucleus
Include B cells, CD4+ helper T cells and CD8+ cytotoxic T cells. Operate primarily in the lymphatic system. Plasma cells produce antibodies

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9
Q

Function and appearance of monocyte

A

kidney shaped nucleus

Phagocytosis of pathogens.
Presentation of antigens to T cells.

Eventually they become tissue macrophages, which remove dead cell debris and attack microorganisms
transform to macrophages

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10
Q

Least common WBC

A

Basophil

0.5-1%

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11
Q

What composition of plasma

A

water, proteins, salt and glucose

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12
Q

Cells of the innate immune system derive from what type of precursor

A

Common myeloid progenitor

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13
Q

Cells of the adaptive immune system derive from what type of precursor

A

Common lymphoid progenitor

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14
Q

3 types of potency

A

Totipotent
pluripotent
multipotent

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15
Q

What is erythropoiesis

A

production of red blood cells start in red bone marrow

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16
Q

What is released by the juxtaglomerular cells in the kidneys in response to hypoxia fro RBC production?

A

Erythropoietin (EPO) released from renal juxtaglomerular cells and some capillaries

17
Q

What is the primary site of heamtopoesis

A

red bone marrow

18
Q

What is yellow marrow

A

It is mainly fat and replaces red bone marrow

19
Q

When can yellow bone marrow be converted to red bone marrow

A

severe bleeding

20
Q

thrombocytes are fragments that come from what

A

Megakaryocytes in red bone marrow

21
Q

What is Anemia

A

low haemoglobin or red blood cells

22
Q

Macrocytic anemia

A

red blood cells are larger than normal
Vit B-12 and folate deficiency
eldery, vegans and alcoholics

23
Q

Microcytic anaemia

A

red blood cells are smaller than normal
iron deficiency anaemia - dietary intake or blood loss
caused by sickle cell disease, thalassemia, and sideroblastic anaemia