Cells of the Blood Flashcards
Function of plasma- what does it help maintain
helps maintain blood pressure and regulates body temperature
function of RBC
transports oxygen and CO2
function of leukocytes
Destroys pathogens, produces antibodies against bacteria and viruses, destroy infected and cancerous cells
function of thrombocytes
prevent bleeding
Function and appearance of Neutrophil
multi lobed nucleus
Bacterial or fungal infection. These are the most common first responders to microbial infection- phagocytosis
Function and appearance of eosinophil
bi-lobed
Parasitic infections and allergic reactions (Inflammatory)
Function and appearance of basophil
bi/tri lobed nucleus
Allergic and antigen response (releases histamine causing vasodilation)
Function and appearance of lymphocyte
deep stained eccentric nucleus
Include B cells, CD4+ helper T cells and CD8+ cytotoxic T cells. Operate primarily in the lymphatic system. Plasma cells produce antibodies
Function and appearance of monocyte
kidney shaped nucleus
Phagocytosis of pathogens.
Presentation of antigens to T cells.
Eventually they become tissue macrophages, which remove dead cell debris and attack microorganisms
transform to macrophages
Least common WBC
Basophil
0.5-1%
What composition of plasma
water, proteins, salt and glucose
Cells of the innate immune system derive from what type of precursor
Common myeloid progenitor
Cells of the adaptive immune system derive from what type of precursor
Common lymphoid progenitor
3 types of potency
Totipotent
pluripotent
multipotent
What is erythropoiesis
production of red blood cells start in red bone marrow
What is released by the juxtaglomerular cells in the kidneys in response to hypoxia fro RBC production?
Erythropoietin (EPO) released from renal juxtaglomerular cells and some capillaries
What is the primary site of heamtopoesis
red bone marrow
What is yellow marrow
It is mainly fat and replaces red bone marrow
When can yellow bone marrow be converted to red bone marrow
severe bleeding
thrombocytes are fragments that come from what
Megakaryocytes in red bone marrow
What is Anemia
low haemoglobin or red blood cells
Macrocytic anemia
red blood cells are larger than normal
Vit B-12 and folate deficiency
eldery, vegans and alcoholics
Microcytic anaemia
red blood cells are smaller than normal
iron deficiency anaemia - dietary intake or blood loss
caused by sickle cell disease, thalassemia, and sideroblastic anaemia