clotting cascade Flashcards
1
Q
what are the vitamin K dependent stages
A
2,7,9,10
2
Q
what are the two factors of extrinsic pathway
A
7
tissue factor (TF)
7 activated then tissue factor is the molecule used to catalyse reaction to make catalyst of 10 to 10A
3
Q
extrinsic pathways is associated with what
A
trauma
4
Q
intrinsics pathway is associated with what
A
damaged surface - kininogen
5
Q
intrinsic pathway factors
A
12,11,9,8
6
Q
what does activated factor 8 do - same as TF
A
catalyses 10 to 10A
7
Q
haemophilia B is associated with what factor
A
9
8
Q
haemophilia A is associated with which factor
A
8
9
Q
VWD is associated with which factor
A
8
10
Q
what factor catalyses prothrombin(2) to thrombin
A
5
11
Q
Thrombin (2a) catalyses what
A
fibrinogen to make fibrin
12
Q
what factor is the last factor used to make a cross-linked fibrin clot
A
factor 13A
