Ovarian Hyperstimulation Syndrome

Question 1

In what situations is ovarian hyperstimulation syndrome seen (OHSS)?

Answer 1

It is a complication of infertility treatment.

Question 2

What happens physiologicaly in ovarian hyperstimulation syndrome?

Answer 2

• Multiple luteinized cysts occur in the ovaries
• Causes by High levels of:
  
  • Oestrogen
  • Progesterone
  • VGEF
• Increased membrane permeability and loss of fluid from the intravascular compartment.

Question 3

What % of women having infertility treatment have suffered from OHSS?

Answer 3

30%

Question 4

Which treatments are more likley due cause OHSS?

• Clomifene
• HCG
• Gonadotropins

Answer 4

HCG and Gonadotropins

Question 5

What is the RCOG classification of mild OHSS?

Answer 5

• Abdominal pain
• Abdominal bloating

Question 6

What is the RCOG classification of moderate OHSS?

Answer 6

• Abdominal pain
• Bloating
• N&V
• USS evidence of ascites

Question 7

What is the RCOG classification of severe OHSS?

Answer 7

• Abdominal pain
• Bloating
• N&V
• USS evidence of ascities
• Clinical evidence of ascites
• Oliguria
• Haematocrit >45%
• Hypoproteinaemia

Question 8

What is the RCOG classification of critical OHSS?

Answer 8

• Abdominal pain
• Bloating
• N&V
• USS evidence of ascities
• Clinical evidence of ascites
• Oliguria
• Haematocrit >45%
• Hypoproteinaemia
• Thromboembolism
• Acute respiratory distress syndomre
• Anuria
• Tense ascites