Endometrial Cancer Flashcards
1
Q
What % of endometrial cancer is seen before menopause?
A
25%
2
Q
What are the risk factors for endomentrial cancer?
A
- Unopposed oestrogen. The addition of a progestogen to oestrogen reduces this risk (e.g. In HRT). The BNF states that the additional risk is eliminated if a progestogen is given continuously
- Obesity
- Nulliparity
- Early menarche
- Late menopause
- Diabetes mellitus
- Tamoxifen
- Polycystic ovarian syndrome
3
Q
What is protective for endometrial cancer?
A
COCP
4
Q
What is the classic post menopausal symptoms for endometrial cancer?
A
Post menopausal bleeding
5
Q
In pre-menopausal women, whatpresentation might they have?
A
Intermenstrual bleeding
6
Q
Will women with endometrial cancer also present with pain and discharge?
A
No, they are unusual features
7
Q
What investigations should be done for endometrial cancer?
A
- First line - TVUS
- Hysteroscopy with endometrial biopsy
8
Q
What is the normal endometrial thickness? (important for understanding USS reports)
A
< 4 mm
9
Q
How is endometrial cancer managed?
A
- Localised disease - total abdominal hysterectomy with bilateral salpingo-oophrectomies. +/- radiotherapy if high-risk disease.
- Progestogen therapy can be used in frail elderly women if not suitable for surgery.
10
Q
What is the prognosis for endometrial cancer?
(good or bad)
A
Good.
It is usually picked up early due to the presentation.
