Marie Stopes Abortion Training Flashcards

1
Q

What is Mifepristone?

A

A Progesterone Receptor Modulator

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2
Q

How does Mifepristone Work?

A
  1. It blocks progesterone
  2. It stops the pregnancy from forming
  3. It causes the placenta and embryo to detach from the uterus
  4. It causes the cervix to dilate
  5. It sensitises the Uterus myometrium to prostaglandins so that the myometrium can contract more effectively.
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3
Q

How many hours after the ingestion of Mifepristone, is the maximal pharmacological effect?

A

36-48 hours

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4
Q

Why do we give Mifepristone?

A

It allows a lower dose of prostaglandin to be used, thus reducing side effects.

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