Ovarian Cancer Flashcards

1
Q

What is the epidemiology of ovarian carcinoma?

A

1:2500 women >55yrs

Rare but more women die due to late presentation

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2
Q

What are the risk factors of ovarian carcinoma?

A
  • BRCA gene
  • Late menopause
  • Nulliparous
  • Subfertility treatment
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3
Q

What are protective factors against ovarian carcinoma?

A
  • COCP/HRT
  • Breast feeding
  • Hysterectomy
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4
Q

What are the clinical features of ovarian carcinoma?

A
Vague symptoms
Bloating
Abdominal distension/pain
Loss of appetite
Weight loss
Fatigue
Change in bowel habits
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5
Q

What are investigations are there for ovarian carcinoma?

A

2 week referral for pelvic mass/ascites

BLOODS
<40yrs = Ca125, alpha-fetoprotein, beta-HCG

IMAGING
-Urgent abdominal and pelvic US

SURGICAL
-Laparotomy w/ biopsy

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6
Q

How is ovarian cancer managed?

A

Adenocarcinomas treated w/ chemotherapy (6 months post op) & surgery

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