ovarian cancer Flashcards
1
Q
pathophysiology of ovarian cancer
A
90% epithelial origin, due to serous carcinomas
2
Q
risk factors for ovarian cancer
A
family history: BRCA1 or 2 gene
many ovulations: early menarche, late menopause, nulliparity
3
Q
clinical features of ovarian cancer
A
vague
abdo distention and bloating
abdo and pelvic pain
urinary symptoms
early satiety
diarrhoea
4
Q
investigations for ovarian cancer
A
CA125
- > ultrasound scan of abdomen and pelvis
usually involves diagnostic laparoscopy
5
Q
management of ovarian cancer
A
combination of surgery and platinum based chemo
