other lymphoprolifera tive Flashcards
characterized by small B lymphocytes with abundant cytoplasm and fine (“hairy”) cytoplasmic projections. The postulated cell of origin is the peripheral B cell of post– germinal center stage (memory B cell).
a. hairy
b. mantle lymphoma
a.Hairy Cell leukemia
is a lymphoproliferative disorder characterized by medium-sized lymphoid cells with irregular nuclear outlines derived from the follicular mantle zone
✓ lymph nodes show a replacement of normal nodal architecture with a diffuse proliferation of
monotonous, medium-sized lymphoid cells with irregular nuclear outlines
b. mantle lymphoma
**a originates from germinal center B cells and in most cases recapitulates follicular architecture **
a. hairy
b. mantle lymphoma
c. Follicular Lymphoma
d. Burkitt Lymphoma
c. Follicular Lymphoma
-composed of small to medium-sized lymphoid cells with irregular nuclear outlines
(cerebriform nuclei)
a. Sezary cells
b. ✓ Sézary syndrome
a. Sezary cells
by definition a disseminated disease with leukemic presentation and skin and lymph node involvement
a. Sezary cells
b. ✓ Sézary syndrome
b. ✓ Sézary syndrome
**✓ Malignant lymphoma but differs in that the cells reacting to the neoplasm predominant rather than the neoplastic cells themselves **
a. Sezary cells
b. ✓ Sézary syndrome
c. Hodgkin’s lymphoma
c. Hodgkin’s lymphoma
**= based to histologic appearance of the involved tissue from lymph node biopsy **
a. Rye classification of Hodgkin
b. Ann Arbor classification of Hodgkin
a. Rye classification of Hodgkin
Most widely used staging scheme,depends on
histologic type and the extent of tissue involvement
a. Rye classification of Hodgkin
b. Ann Arbor classification of Hodgkin
b. Ann Arbor classification of Hodgkin