OTHER LYMPHOID MALIGNANCIES Flashcards
Monoclonal gammopathy causes B cell production of excessive IgG or IgA
A. Multiple Myeloma
B. Waldenstrom macroglobulinemia
A. Multiple Myeloma
Monoclonal gammopathy caused B cell production of excess IgM (macroglobulin) and decreased production of the other immunoglobulins
A. Multiple Myeloma
B. Waldenstrom macroglobulinemia
B. Waldenstrom macroglobulinemia
- Identified on serum protein electrophoresis by
an “M:-spike in the gamma globulin region - Bone tumors
A. Multiple Myeloma
B. Waldenstrom macroglobulinemia
A. Multiple Myeloma
- Bence jones proteins (free light chainskappa or lambda) – observe white precipitation depending on temperature
A. Multiple Myeloma
B. Waldenstrom macroglobulinemia
A. Multiple Myeloma
-Lymphadenopathy and
hepatosplenomegaly
- Increased blood viscosity
No bone tumors
A. Multiple Myeloma
B. Waldenstrom macroglobulinemia
B. Waldenstrom macroglobulinemia