ACCORDING TO FAB

Question 1

Acute Lymphoblastic Leukemia
According to FAB

Answer 1

L- CHILDREN

,L2,(OLDER CHILDREN AND ADULT)

L3- PATIENTS WITH LUKEMIA SECONDARY TO BURKITT LYMPHOMA

Question 2

is the most common cancer in children, representing 23% of cancer diagnoses among children younger than
15 years of age.

A. ACUTE LYMPHOBLASTIC LEUKEMIA
B. CHRONIC LYMPHOBLASTIC LEUKEMIA

Answer 2

A. ACUTE LYMPHOBLASTIC LEUKEMIA

Question 3

small in size with same shape, lymphoblasts nucleus and scanty cytoplasm

A. L1
B. L2
C. L3

Answer 3

A. L1

Question 4

large lymphoblast and heterogenous when viewed in PBS; cleft nuclei

A. L1
B. L2
C. L3

Answer 4

B. L2

Question 5

(patients with leukemia secondary to Burkitt’s Lymphoma) – white holes in the lymphoblasts, EBV virus

A. L1
B. L2
C. L3

Answer 5

C. L3

Question 6

FAB ALL

* Differentiated based on morphology including:

Answer 6

“CPA”

⮚cell size
⮚ prominence of nucleoli
⮚ amount and appearance of cytoplasm

Question 7

Lymphoblasts are small and homogenous, varies little in size

A ALL L1
B. ALL L2
C. ALL L3

Answer 7

A ALL L1

Question 8

Lymphoblasts are large and heterogenous, variable in size

A ALL L1
B. ALL L2
C. ALL L3

Answer 8

B. ALL L2

Question 9

Scanty cytoplasm and inconspicuous nucleoli; nucleus is round and
irregular/indistinct in shape; L ratio; most common CHILDHOOD ALL
with best prognosis

A ALL L1
B. ALL L2
C. ALL L3

Answer 9

L1

Question 10

Abundant, basophilic cytoplasm, and the nuclei are often clefted with nucleoli present
Adult type AL

A ALL L1
B. ALL L2
C. ALL L3

Answer 10

B. ALL L2

Question 11

 Burkitt-type
 Lymphoblasts are large, homogenous and vacuolated

A ALL L1
B. ALL L2
C. ALL L3

Answer 11

C. ALL L3

Question 12

**Rarest ssubclass, can be found in both children and adult

 Poor prognosis

A ALL L1
B. ALL L2
C. ALL L3

Answer 12

C. ALL L3