LYMPHOMAS Flashcards
includes the various forms of leukemias and malignant lymphomas that are of lymphoreticular origin.
A.LYMPHOMAS
B. HODKIN Lymphomas
C. Lymphoproliferative disorder
C. Lymphoproliferative disorder
group of closely related disorders that are characterized by the overproliferation of one or more types of cells of the lymphoid system such as lymphoreticular stem cells, lymphocytes, reticular cell
and histocytes
A.LYMPHOMAS
B. HODKIN Lymphomas
C. Lymphoproliferative disorder
A.LYMPHOMAS
TEST USED FOR DETECTION OF LYMPHOMA
* TISSUE BIOPSY= SPLEEN
CD SURFACE MARKERS
** CYTOGENETICS OR DNA TRUGH PCR **
preferred because of recent discoveries establishing the origin/hallmark of the *Reed-Sternberg cell
in almost all cases of Hodgkin disease as the B-lymphocyte
A. Hodgkin Lymphom
B. Non-Hodgkin Lymphoma
A. Hodgkin Lymphom
● Aneuploidy, or a deviation from the diploid number of chromosomes.
● A gain of chromosomes 1, 2, 5, 12, and 21 is a recurring numerical abnormality
A. Hodgkin Lymphom
B. Non-Hodgkin Lymphoma
A. Hodgkin Lymphom
NORMAL CHROMOSOME
A. 46
B47
C. 45
A. 46
** trisonomy**
A. 46
B47
C. 45
B47
Monosomy
A. 67
B. 45
C.43
B. 45
Most frequent type of Non- Hodgkin Lymphoma is
a. diffuse large B-cell lymphoma.
b. diffuse large T-cell lymphoma.
a. diffuse large B-cell lymphoma.
Three different types of diffuse large B-cell lymphomas
- Germinal center-B-cell–like lymphoma
- Activated B-cell-like lymphoma
- New subgroup, type 3 diffuse large B-cell lymphoma
40% of lymphomas
a. hodgkin
b. non-hodgkin
a. hodgkin
associated with epstein-barr virus
a. hodgkin
b. non-hodgkin
a. hodgkin
reed-sternberge cells (rs)
a. hodgkin
b. non-hodgkin
a. hodgkin
b cell lineage
a. hodgkin
b. non-hodgkin
a. hodgkin
b cell neoplasm
a. hodgkin
b. non-hodgkin
b. non-hodgkin