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PART 4: ACUTE LYMPHOBLASTIC LEUKEMIA > additional notes > Flashcards

additional notes Flashcards

1
Q

Marker for primary granules
of auer rods

a. Sudan Black B
b. Myeloperoxidase
c. Terminal
deoxyribonucleoti
dyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue

A

Myeloperoxidase

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2
Q

Marker for phospholipids
and lipids
a. Sudan Black B
b. Myeloperoxidase
c. Terminal
deoxyribonucleoti
dyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue

A

a. Sudan Black B

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3
Q

-Activity results in bright fuchsia pink or magenta red Pattern of staining varies with each cell type

-Lymphoblastic leukemia shows
blocky or chunky pattern L1 and L2 block
pattern **
-Erythroblasts in M6 leukemia is positive**

a. Sudan Black B
b. Myeloperoxidase
c. Terminal
deoxyribonucleoti
dyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue

A

d. Periodic Acid Schiff

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4
Q

Is present in 90% cases
of ALL
Used to differentiate AML to ALL

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue

A

c. Terminal deoxyribonucleotidyl transferase

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5
Q

Marker for mature and
immature neutrophils
and mast cells

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue

A

e. Naphthol AS-D chloroacetate Esterase

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6
Q

Marker for monocytes,
megakaryocytes, and
plasma cells

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue

A

Alpha- napthyl acetate esterase

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7
Q

Identifying monocytes,
promonocytes, and
monoblasts

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue
j. Alpha- naphthyl Butyrate esterase

A

j. Alpha- naphthyl Butyrate esterase

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8
Q

Present in all
hematopoietic cells and
found on lysosomes

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue
j. Alpha- naphthyl Butyrate esterase
k. acid phosphatase

A

k. acid phosphatase

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9
Q

Marker for hairy cell leukemia

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue
j. Alpha- naphthyl Butyrate esterase
k. acid phosphatase

A

g.Tartrate resistant acid phosphatase

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10
Q

Neutrophils is the only
leukocyte that contain
this activit

Used to differentiate CML from a leukamoid reaction

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue
j. Alpha- naphthyl Butyrate esterase
k. acid phosphatase

A

Leukocyte alkaline Phosphatase (LAP)

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11
Q

Strongly metachromatic
Useful for recognition of mast cells and tissue basophils

Binds with acid mucopolysaccharides in blood cells

a. Sudan Black B
b. Myeloperoxidase
c. Terminal deoxyribonucleotidyl transferase
d. Periodic Acid Schiff
e. Naphthol AS-D chloroacetate Esterase
f. Alpha- napthyl acetate esterase
g.Tartrate resistant acid phosphatase
h.Leukocyte alkaline Phosphatase (LAP)
i.Toluidine Blue
j. Alpha- naphthyl Butyrate esterase
k. acid phosphatase

A

i.Toluidine Blue

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PART 4: ACUTE LYMPHOBLASTIC LEUKEMIA (12 decks)

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