MORPHOLOGICAL ABNORMALITIES IN PERIPHERAL BLOOD AND BONE MARROW Flashcards
Oval macrocytes
**Hypochromic microcytes **
Dimorphic red blood cell (RBC) population
RBC precursors with more than one nucleus
RBC precursors with abnormal nuclear shapes
RBC precursors with uneven cytoplasmic staining
Ring sideroblasts
a.Dysmyelopoiesis
b.Dyserythropoiesis
c. Dysmegakaryopoiesis
b.Dyserythropoiesis
Giant platelets
Platelets with abnormal granulation
Circulating micromegakaryocytes
Large mononuclear megakaryocytes
Micromegakaryocytes or micromegakaryoblasts or both
Abnormal nuclear shapes in the megakaryocytes/megakaryoblasts
a.Dysmyelopoiesis
b.Dyserythropoiesis
c. Dysmegakaryopoiesis
c. Dysmegakaryopoiesis
Persistent basophilic cytoplasm
Abnormal granulation
Abnormal nuclear shapes
Uneven cytoplasmic staining
a.Dysmyelopoiesis
b.Dyserythropoiesis
c. Dysmegakaryopoiesis
a.Dysmyelopoiesis