CHEMOTHERAPY AGENTS ARE CATEGORIZED AS

Question 1

⮚ ionize within cells, forming highly reactive free radicals that
damage DNA
⮚ These agents act on any phase of the cell.

a. Alkylating agents
b.Plant alkaloids
c. Antitumor antibiotics

Answer 1

a. Alkylating agents

Question 2

⮚ They include such drugs as nitrogen mustard, cyclophosphamide, chlorambucil, busulfan, and melphalan (Alkeran)

a. Alkylating agents
b.Plant alkaloids
c. Antitumor antibiotics

Answer 2

a. Alkylating agents

Question 3

Affect microtubules and interrupt the process of mitotic spindle formation during the metaphase stage of mitosis.
⮚ These agents include vincristine and vinblastine

a. Alkylating agents
b.Plant alkaloids
c. Antitumor antibiotics

Answer 3

b.Plant alkaloids

Question 4

⮚ Compounds derived from living microorganisms are termed antibiotics, and some have antitumor effects.
⮚ Antibiotics inhibit RNA and DNA synthesis and interfere with the G2 phase of the cell cycle.

a. Antitumor antibiotics

b. Alkylating agents
c.Plant alkaloids

Answer 4

a. Antitumor antibiotics

Question 5

Commonly used tumor antibiotics in antitumor

a. daunonubicin and doxorubicin (Adriamycin)
b. cyclophosphamide, chlorambucil, busulfan,

Answer 5

a. daunonubicin and doxorubicin (Adriamycin)

Question 6

vincristine and vinblastine.

a. Plant alkaloids
b.Glucocorticoids

Answer 6

a. Plant alkaloids

Question 7

⮚ Interfere with the normal functions of various essential metabolites

a. Plant alkaloids
b.Glucocorticoids
c. antimetabolites

Answer 7

c. antimetabolites