Other Flashcards

1
Q

Cyclophosphamide MoA?

A

Kill cancer cells; inhibit protein synthesis and cross-link DNA/RNA stands

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2
Q

Cyclophosphamide I?

A
Malignant disease (multiple myeloma, malignant lymphoma, leukemias, breast carcinoma etc.)
Nephrotic syndrome
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3
Q

Cyclophosphamide CI?

A

HSR severe history

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4
Q

Oral steroids MoA?

A

Decrease inflammation by the suppression of polymorphonuclear leukocyte migration and reverse increased capillary permeability and suppress immune system

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5
Q

Oral steroids CI?

A

TB active/inactive, diabetes, infection

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6
Q

Oral steroids x4 examples?

A

Prednisolone, dexamethasone, hydrocortisone, betamethasone

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7
Q

How do you offset the osteoporosis risk when taking oral steroids?

A

Bisphosphates taken

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8
Q

Oral steroids CI?

A

TB active/inactive, diabetes, infection

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9
Q

Atracium I?

A

General anesthesia for skin muscle relaxation and mechanical ventilation

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10
Q

Atracium SE?

A

Allergic reaction, hypotension

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11
Q

Hormone replacement therapy MoA?

A

Replace estrogen lost due to the menopause

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12
Q

CI of HRT?

A

PTE history, breast cancer history, liver disease

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13
Q

HRT I?

A

Alleviate the symptoms of the menopause

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