OTC Exam 1 Flashcards
What are special populations in OTC
Pregnant
Geriatric
Pediatric
Lactating
Who does the FDA recommend against self medicating with nonprescription products
Children less than 2 years old
What type of dosing is preferred
Weight based
What are exclusions for self treatment
- OTC not available or recommended for child’s age group
- disorder not self treatable because of age
- rarity condition
- could indicate more serious disorder
What are administration considerations
Taste and measuring device
What dosage forms are available for acetaminophen
Capsules
Tablets
Chewable tablets
Liquid
Suppositories
ODT
What dosage forms are available for ibuprofen
Capsules
Tablets
Chewable tablets
Liquid
What dose do acetaminophen chewable tablets come in
160 mg with score (80 mg sections)
What is the concentration of acetaminophen liquid
160 mg/5 mL
What is the infant concentration of ibuprofen
50 mg/1.25 mL (40 mg/mL)
What is the concentration of child’s ibuprofen
100 mg/5 mL
What pediatric antihistamines are available in chewable
Cetirizine
Diphenhydramine
Loratadine
What pediatric antihistamine is not available in a chewable tablet
Fexofenadine
What should miralax NOT be mixed in
Milk
What drugs are generally not recommended in pediatrics
Codeine
Promethazine
Quinolones
Tetracycline
Why is codeine not recommended in pediatrics
CYP2D6 enzyme converts it to morphine which could cause possible overdose for people who over-express this enzyme
Why is promethazine not recommended in pediatrics
Severe and potentially fatal respiratory depression
Why are quinolones not recommended in pediatric patients
Adverse effect on cartilage, bone, and muscle
Why are tetracyclines not recommended in children younger than 8
Stain teeth and weaken bones
What are the primary causes of accidental overdose in children
Iron and acetaminophen
What is the poison control number
1-800-222-1222
How does ABSORPTION change in the elderly population
- increased GI secretions and motility
- decreased surface area and blood flow
- increased pH
How does DISTRIBUTION change in the elderly population
- decreased total body water
- decreased muscle mass
- increased body fat
How does METABOLISM change in the elderly population
- decreased hepatic blood flow
- decreased enzyme activity
How does ELIMINATION change in the elderly population
Decreased renal function
What PK parameters change as you age
Absorption
Distribution
Metabolism
Elimination
What are the concerns with NSAID use in the elderly population
GI changes
Cardiovascular issues
Renal function concern
What are factors that pharmacists should consider in geriatric patients
- Polypharmacy
- Multiple chronic disorders
- Alteration in senses
- Cognition and memory changes
- Dysphagia
- Sensitivity to anticholinergic meds
- Blurred vision
- decreased Salivation
- decreased Lacrimation
- Urinary retention
- Constipation
(Pharmacy School Sucks, At Least Dumb Bitches Can’t Make Us Cry)
What resource contains meds that cause adverse effects in the elderly
Beer’s criteria
What are screening tools used to adjust medications in the elderly
STOPP/START criteria
What should pregnant patients try first
nondrug therapy
Most medications cross what
The placenta
Most medications cross what
The placenta
What should pregnant patients never presume about an OTC medication
That it is safe for use during pregnancy
When is the best time for a breastfeeding mother to take a medication
Immediately after feeding or right before infant’s longest sleeping period
What should breastfeeding mothers be advised
- use nonpharmacologic therapy if possible
- take medication immediately after nursing/before infant’s longest sleep
- counsel on potential side effects in the infant
What should a breastfeeding mother avoid
Extra strength/long acting products
Combination products
What resource is an A to Z searchable database that summarizes known/possible side effects in pregnancy and possibility of passage through breast milk
Briggs
What drugs are safe for pregnancy for allergic rhinitis
- chlorpheniramine
- diphenhydramine
- cromolyn
- saline NS
- flonase
- zyrtec/claritin/allegra (2nd gen)
(Zack Catches Cute Cats And Dogs [on] Friday, Saturday)
What drugs are unsafe during pregnancy for congestion
Phenylephrine
Pseudoephedrine
What drugs are UNSAFE during pregnancy for pain, fever, and headache
- aspirin (avoid high dose in 1st and 3rd trimesters)
- excedrin
- ibuprofen/naproxen (avoid in 1st and 3rd trimesters)
What drugs are UNSAFE during pregnancy for diarrhea
Loperamide
Pepto (bismuth subsalicylayte)
What drugs are UNSAFE during pregnancy for constipation
Castor oil
Mineral oil
What should be discouraged during lactation
Homeopathic and herbal remedies
What drugs are SAFE during pregnancy for constipation
Miralax
Colace/docusate
Fiber
Sennosides
Bisacodyl