Osteoporosis Therapy: Mixed Estrogen Agonist/Antagonists Flashcards
1
Q
Mixed estrogen agonist/antagonist drug
A
Raloxifene
2
Q
Raloxifene MoA
A
Decreases resorption of bone and bone turnover, increases BMD, and decreases fracture incidence
3
Q
Raloxifene dosing
A
60mg PO QD
4
Q
Raloxifene ADEs
A
Hot flashes, leg cramps, peripheral edema, gallbladder disease, cataracts (rare)
5
Q
Raloxifene BBW
A
VTE, stroke
6
Q
Raloxifene is for…
A
…FEMALES ONLY!
7
Q
Raloxifene indication
A
Post-menopausal osteoporosis and reduction in risk of invasive breast cancer in post-menopausal women with osteoporosis
8
Q
Raloxifene is an…
A
…antiresorptive agent
