Osteology Flashcards
What are the four basic tissues of the human body?
Epithelial
Muscle
Neural
Connective
What is osteology?
The study of bone
What are the three primary cell types of bone?
Osteoblasts
Osteocytes
Osteoclasts
What is the function of each type of bone cell?
Osteoblast = form bone Osteocyte = maintain or nurture bone Osteoclast = remodel bone
What are the bone cells embedded in?
An amorphous matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
Glycosaminoglycans
What types of glycosaminoglycans predominate in bone?
Chondroitin sulfates
Keratin sulfates
Hyaluronic acid
What is the principal type of protein fiber in bone?
Collagen type I
What are the primary constituents of the bone mineral?
Calcium ions
Phosphate ions
Citrate ions
Carbonate ions
What is the most frequently described deposit in bone?
Hydroxyapatite
Bone is also the repository for what additional ions?
Sodium Magnesium Fluoride Lead Strontium Radium
What is Wolff’s Law as it pertains to bone?
Living tissue will respond to stressors; bone is formed or absorbed in response to stress
What are the three responses of bone that allow it to be described as “living”?
It has the ability to heal, to remodel under stressors and age
What is bone the embryological derivative of?
Mesenchyme
Cartilage
What is the name given to the pattern of ossification in mesenchyme?
Intramembranous ossification
What is the timing for the appearance of intramembranous ossification?
From the second to third month in utero
What bones are derived from intramembranous ossification?
Nasal, palatine, vomer, lacrimal, zygomatic, maxilla, frontal, parietal, most of mandible and clavicle, squama of the temporal and occipital bone, greater wing of the sphenoid
Which bones of the neurocranium are formed by intramembranous ossification?
Frontal, parietal, squama of temporal and occipital bones, greater wing of sphenoid
What is the name given to the pattern of ossification in cartilage?
Endochondral ossification
What is the timing for the appearance of ossification in cartilage?
From the second to fifth month in utero
What part of the skull is derived from endochondral ossification?
Chondrocranium
Which bone of the appendicular skeleton is formed by both endochondral and intramembranous ossification?
The clavicle
What are the names given to the centers of ossification based on time of appearance?
Primary centers of ossification appear before birth
Secondary centers of ossification appear after birth
Mature bone is described as being composed of what areas based on bone density?
Cortical or compact bone and spongy, cancellous, or trabecular bone
What is the name given to the below the articulating surface?
Subchondral bone
What is the name of the outer fibro-cellular covering of bone?
The periosteum
What is the name given to the fibro-cellular lining of bone?
The endosteum