Opthalmology Flashcards
What is leukocoria and what is indicative of?
Leukocoria is abscence of red reflex “becoming white”
Indicative of tumor (retinoblastoma)
What is the most common intraocular malginancy in children under the age 4
Retinoblastoma
What is the clinical presentation of retinoblastoma
- leukocoria
- strabismus
- poor vision
- red painful eye
- proptosis
What is the finding in the imaging for retinoblastoma?
Calcifications within tumor
What is the imaging modality of choice for retinoblastoma?
MRI brain and orbit
“Never CT”
What are the goals of RB therapy?
Preservation of
1- Life
2- Globe
3- sight
What is the treatment of choice in RB?
- Enucleation (large - optic nerve affected)
- laser (stop vasculature)
- cryotherapy (freeze) +- chemotherapy (ocular\intra arterial)
- external beam radiotherapy
What is the follow up plan for retinoblastoma?
- Every 4-6w for EUA
- for RB1 genetic type
- systemic follow up for metastasis
In RB familial type, we should find
RB1 gene
Are the patients with sporadic RB have any genetic mutation
No
What is cataract
Opacification of lens
What is the most common inheretence of cataract in KSA
AR
What are the associated systemic disease in cataract?
1- galactosemia
2- hypoocalcemia
3- wilson
4- diabetes
What are the chromosomal abnormalities associated in Catarct
- down
- patau
What will you do if you see bilateral cataract
Intensive workup
- TORCH screening
- Syphilis (VDRL)
- Calcium levels
- Phosphorus
- glactokinase
- glucose
- urine for reducing substance
What will you see if you see unilateral cataract?
Bring them to OR immidiatly
What does the management of cataract depen on?
The size - laterality
How to treat cataract ( in general)
- lensoctomy
- optical correction
In small cataract what would you like to do next?
cover and Observe
However if i cover for long time i risk the development of ampylopia
If the child is more than 1 year, what will we do in case of catarct?
Lens aspiration + IOL
“If less we don’t do IOL”
If the child was less than 1 year of age, and we did not introdue IOL. what will we do
Provide a high power glassess
To avoid formation of posterior membranes, what surgical intervention should we do in cataract
Posterior capsulotomy and anterior viterctomy
What do you expect to see in glucoma?
- megalocornea
- Haabs striae
- opacity and haze
- corneal edema\scar
What is the clinical presentation of primary congenital glucoma?
- Epiphorea (tearing)
- Blephrospasm (blinking)
- Photophobia
What is the IOP in glucoma?
> 21mmhg increased
What causes opacity of the cornea?
Increased IOP will cause edema and it will go in the corena
What is the poor outcome of glucoma if IOP was not corrected in early childhood
Optic nerve damage leading to loss of sigth
What will you find in glucoma in fundoscopy examination
Cupping
When can we do surgery in glucoma
After 4-6 weeks of life, usually we do multiple
When is retinopathy of prematurity?
<31 weeks of gestation
What is the pathophysiology of ROP?
Cessation of vasculogensis after birth > VEGF release causing either
- resuming normal process
- abnormal proliferation leading to retinal detachment
What are the risk factors for ROP?
- LBW <1500
- <30 wks
- Supplemental O2
- Coexisting illness rds-sepsis
- Caucation
- multiples