Opioids Flashcards

1
Q

Sigma receptors for opioids

A

adverse effects (dysphoria, excitement, anxiety, restlessness)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of drugs are best for severe pain

A

Agonists (opioids)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which opioid agonist is the gold standard that all other opioid agonists are compared to

A

Morphine (caution in cats: different metabolism)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which opioid agonist is 5-7 x more potent than morphine, and has fewer side effects

A

Hydromorphone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Antitussive (butorphanol)

A

Cough suppressant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is buprenorphine (partial mu agonist/ kappa antagonist) good for

A

Moderate pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is butorphanol (kappa agonist/ mu antagonist) good for

A

Mild to moderate pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is tramadol good for (synergistic w NSAIDS)

A

Moderate pain (allodynia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is an opioid antagonist

A

Reversal agent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are three opioid antagonist agents

A
  1. Naloxone
  2. Nalmefene
  3. Naltrexone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly