Immune Reactions

Question 1

Type ll immune reaction is a ___________ _____________ ______________ event

Answer 1

Antibody mediated cytotoxic event

Question 2

What two conditions that affect blood cells are considered type ll (antibody mediated cytotoxic immune reactions)

Answer 2

IMHA: Immune Mediated Hemolytic Anemia
IMTP: Immune Mediated Thrombocytopenia

Question 3

Pemphigus complex is a type ll (antibody mediated cytotoxic) immune reaction that affects the ____________

Answer 3

Skin

Question 4

Type ll (antibody mediated cytotoxic) immune reaction that results in antibodies against acetylcholine receptors

Answer 4

Myasthenia gravis

Question 5

What is acetylcholine

Answer 5

A neurotransmitter of the Parasympathetic nervous system

Question 6

What is the most common type ll immune reaction

Answer 6

Immune Mediated Hemolytic Anemia
IMHA

Question 7

Primary IMHA is usually seen in dogs, while secondary IMHA is usually seen in cats. How is IMHA diagnosed 3

Answer 7

1. CBC
2. Agglutination
3. Coombs test

Question 8

Common complication of IMHA

Answer 8

Thromboembolism

Question 9

Myasthenia gravis results in antibodies that block transmission of acetylcholine on muscles resulting in muscle weakness that gets worse with exercise. This primarily affects __________ muscles and the __________

Answer 9

Affects skeletal muscles and the esophagus (mega esophagus)

Question 10

Diagnosis of myasthenia gravis 2

Answer 10

1. Ach antibodies in serum
2. Tensilon test (Anticholinesterase)