Ondansetron

Question 1

Ondandetron Mechanism of action

Answer 1

Blocks serotonin receptors in the brain and peripherally in the gastrointestinal tract.

Reduces nausea and vomiting

Question 2

Ondansetron Indicated for

Answer 2

Clinically significant nausea and vomiting

Question 3

Ondansetron Contraindications

Answer 3

Known severe allergy

Aged less than 1 year

Question 4

Ondansetron Cautions

Answer 4

Prolonged QT syndrome (fast chaotic heart beats)

Question 5

Ondansetron pregnancy and breast feeding

Answer 5

May be administered if nausea or vomiting is severe

May be administered while breast feeding

Question 6

Ondansetron Dosage

Answer 6

8mg oral for patient 12 years and over - 2 wafers

IM and IV 4mg for patients 12 years and over.

Question 7

Ondansetron common adverse effects

Answer 7

Headache

Flushing

Metallic taste

Question 8

Ondansetron Onset of effect

Answer 8

Oral 10 - 20 minutes

IV 2 - 5 minutes

IM 5 - 10 minutes

Question 9

Ondansetron Duration of effect

Answer 9

4 - 8 hours

Question 10

Ondansetron Usual preparation

Answer 10

4mg wafers

IM and IV not applicable to EMT