Oncology- peds Flashcards
TNM staging
T= primary tumor TX= can't be measured T0= can't be found Tis= in situ T1-4= size and spread into structures
N= lymph nodes NX= can't be evaluated N0= no involvement N1-3= size, location, and/or number of lymph nodes affected
M= metastasis M0= no distant met M1= distant met
Acute lymphocytic leukemia (ALL)- epidemiology
2-5yr
Most common
Acute lymphocytic leukemia (ALL)- s/s
Lymphadenopathy Fever Hepatosplenomegaly (HSM) Fatigue Pallor Bruising/bleeding Bone pain/limp/tenderness Painless testicular enlargement Malaise
Acute lymphocytic leukemia (ALL)- dx
BMB/A >20%
Acute lymphocytic leukemia (ALL)- labs & imaging
CBC w diff and peripheral smear:
Anemia
Thrombocytopenia
Blasts
Acute lymphocytic leukemia (ALL)- tx
Chemo- determined by phenotyping
Acute lymphocytic leukemia (ALL)- prognosis
5 yr > 85%
CNS tumors- epidemiology
2nd most common
CNS tumors- s/s
HA Irritable N/V Macrocephaly Ataxia/impaired gait Impaired vision Seizure Papilledema Developmental delay
CNS tumors- dx
8x- histologic
CNS tumors- labs & imaging
MRI
CNS tumors- tx
Open surgical procedure - get biopsy and remove as much as possible
Avoid radiation <3yo
Chemo
Anticonvulsants - seizures
CNS tumors- prognosis
Depends on tumor type
5y >73%
Retinoblastoma- epidemiology
0-2yr
50% heritable - increased chance of passing to kids, and bilateral issues
Retinoblastoma- s/s
“Leukocoria
Strabismus, red inflamed eye, nystagmus”