Disorders Of Hemoptysis Flashcards
Bleeding and clotting
Coag- process by which blood clots via coag cascade
Disorders—> bleeding or obstructive clotting
Bleeding time
Plt eval- how long did it take the pt to clot
Activated partial thrombophlebitis time (aPTT)
Evals the intrinsic pathway
Increase in heparin use, hemophilic, DIC, APS
Prothrombin time (PT)
Evals the extrinsic pathway
Increase in warfarin use, liver dysfunction, Vit K def, DIC
Fibrinogen
Protein precursor in fibrin
Decrease= greater bleeding risk
D-dimer
Product of clot breakdown
Coag factors
Factor VIII, vWF
Hemostasis- mechanisms: primary
Plt adhesion
Activation
Aggregation creates hemostatic plug
Hemostasis- mechanisms: secondary
Clotting factors are activated to form a fibrin complex- stabilizes platelet plug
Hemostasis- mechanisms: liver
If it doesn’t work—> increase bleeding events