ONCOLOGY; INTEGUMENTARY SYSTEM Flashcards
Define each:
Neoplasia
Oncology
Neoplasia - new growth
Oncology – study of tumors or neoplasia
Define each:
Tumor
Cancer
Tumor - swelling - benign
Cancer - malignant
Extent to which neoplastic parenchymal cells
resemble the corresponding normal parenchymal
cells both morphologically and functionally
DIFFERENTIATION
LACK/LOSS of differentiation, associated with other morphologic changes
ANAPLASIA
ANAPLASTIC CHANGES (4)
PLEOMORPHISM
ABNORMAL NUCLEAR MORPHOLOGY
LOSS OF POLARITY, DISTURBED ORIENTATION
TUMOR GIANT CELLS
loss in uniformity & architectural orientation of the cells
Disordered growth, often occurs in metaplastic epithelium
More of a precancerous stage
Reversible
DYSPLASIA
Abnormal mass of tissue
Growth exceeds and uncoordinated with tha kd the niemal tissue
Autonomous
Clonal-arise from single cell that incurred Generic damage
NEOPLASIA
Define each
GRADING
STAGING
GRADING - degree of differentiation of tumor cells and the number of mitosis (microscopic description)
STAGING - based on size of primary lesion, extend of regional
Located at the ends of chromosomes
Functions:
Protect chromosomes from dergrations
Regulates telomerase activity at chromosomes ends
Essensial for chromosome stability
Telomeres
Invasion vs metastasis
Invasion – Direct extension
Metastasis – Distant from the primary site
This skin lesion is associated with patients infected with HIV
Kaposi sarcoma
A skin lesion characterized by presence of watery fluid inside is
bullae
This skin infection is marked by presence of yeast cells and hyphal elements
fungal
This skin lesion rarely metastasize
basal cell carcinoma
Pruritus means
itchiness
The UV ray exposure with greater risk for skin cancer is
UV B
Infection with HTLV increases the risk for
lymphoma
Grading is more significant than staging when dealing with patients’ prognosis
A. TRUE
B. FALSE
B. FALSE