Oncology Flashcards
What are the two types of skin cancers
SCC and BCC
Which skin cancer is the most common
BCC
What skin cancer is the second most common
SCC
What are the common features of a SCC lesion
Sun exposed areas like face and lips
Lesions may look scaling, crusting, red patches, or thickened raised wart like areas with a central depression
What are the RF for SCC
Sun damange skin without actinic keratosis,
Irradation
Scarring and inflammation
Smoking
Arsenic
Immmusupression
HPV
What is the pathophysiology of SCC
UV radiation or other damaging agents will cause DNA damage to squamous cells leading to keratinocyte proliferation which is ATYPICAL
What is the classic sign of Bowens disease
Sun exposed sites with a slow growing, red scaly patch
What is bowen’s disease
It is SCC IN SITU and can progress to full blown SCC
What is the treatment for bowens disease
Cryotherapy, Curretage, Excision or 5-flouracil cream
What is a keratocanthoma
A low grade SCC which presents as rapidly growing tumour in a sun exposed arae
What is actinic keratosis
Rough patches of sun exposed skin with itching
How can actinic keratosis be treated
Cyrotherapy, Exciion, 5-flouracil cream, diclofenac, imiquimod cream
What category of skin cancer does SCC fall under
Non melanoma skin cancer
What is the diagnosis of SCC
Incision/excision biopsy
What is the checklist for melanoma
Major features
- change in size, irregular shape/border/colour
Minor features:
- large diameter >7mm, inflammation, oozing, change in sensation
