Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MRCP > Dermatology > Flashcards

Dermatology Flashcards

1
Q

Granuloma annulare/ necrobiotic papulosis

A

Common in diabetes, hyperlipidemia and autoimmune thyroiditis
Ring/annular shape
Small papules skin colour or pink which are red, and coalesce
Tx: topical/ intralesional corticosteroids, mtx, biological agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Necrobiosis lipoidica

A

Tender
Brown yellow patches
Usually on shins
Ulcerate
diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Psoriasis

A

Scaly plaques
Salmon coloured

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pyoderma gangrenosum

A

AI
Painful, enlarged ulcer - rapid growth
RF: IBD, RA
Tx: debridment, abx, steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Scabies

A

Itchy
Webspaces of fingers and toes
Causes by mites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dermatomyositis symptoms

A

Rash + myositis (inflammation of muscles)
Sx:
Heliotrope rash: red/purple rash around eye with oedema
Gottrons papules: purple rash over knuckles
Proximal myopathy: cant stand up
Shawl sign: Erythema of upper back and neck
Calcification in childrens subtype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dx of dermatomyositis

A

Creatine kinase
AST
LDH
ANA,
Anti-mi-2: SPECIFIC FOR DERMATOMYOSITIS
anti-jo: polymyositis+ lung fibrosis
Muscle biopsy : degeneration, fibrosis, necrosis
Electromyography

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the risk of dermatomyositis

A

Risk of cancer: lung, breast, oesophagus, colon and ovarian
Involuntary muscles affected- dangerous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Treatment of dermatomyositis

A

steroids- pred
Cyclosporine
Azt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ddx of dermatomyositus

A

atopic/contact dermatitis
Periorbita cellulitis
Photosensitivity
SLE
Polymyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What nail changes happen in cutaneous lupus erythematosus

A

Nail fold changes and splinter hemorrhages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What nail changes occur in alopecia areata

A

Pitting and ridging nail changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What nail chnges occur in hypoproteinemia

A

Leukonychia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What nail changes occur in lichen planus

A

Ridging and trachyonychia (nails look sandpapered)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is infliximab prescribed

A

AS INFUSION
works on TNF a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What three drugs work on TNF-A in psoriasis

A

Eternercept- SUBCUT,
Adalimumab- SUBCUT
Inflixmab - INFUSION

17
Q

What three biological agents are human monoclonal antibodies

A

Enternacept
Adalimumab
Ustekinumab

18
Q

Which monoclonal antibody used to treat psorisis is a chimeric

A

INFLIXIMAB

19
Q

Which monoclonal antibody works against IL12 and IL 23

A

Ustekinumab in PSORIASIS

20
Q

Which cytokine is expressed in high levels in psroasis

A

IL 17, drives iflammatory cells and increases active psoriasis

21
Q

What monoclonal antibody is active against IL17

A

Ixekizumab

MRCP (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions