Onc 2 Flashcards by Mani Yavi | Brainscape

Q

hypothalamic nucleus:

circadian rhythm

A

supraoptic

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Q

hypothalamic nucleus:

parasympathetic

A

anterior

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Q

hypothalamic nucleus:

sympathetic

A

posterior

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Q

hypothalamic nucleus:

ADH

A

supraoptic

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Q

hypothalamic nucleus:

oxytocin

A

paraventricular

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Q

hypothalamic nucleus:

gonadotropins

A

preoptic

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Q

vector:

snail

A

schistosoma

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Q

vector:

ixodes

A

babesia

borrelia

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Q

vector:

reduvvid

A

t cruzi

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Q

vector:

anopheles

A

plasmodium

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Q

vector:

sandfly

A

leishmania

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Q

vector:

tsetse

A

trypanosoma

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Q

what drugs cause sulfa allergy

A

celecoxib

loops/ thiazides/ acetozolamide

probenecid

sulfa-

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Q

benign tumor of epithelium

A

adenoma

papilloma

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Q

malignant tumor of blood vessels

A

angiosarcoma

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Q

benign tumor of bone

A

osteoma

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Q

malignant tumor of smooth muscle

A

leiomyosarcoma

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Q

what unique enzyme is present in cancer and stem cells

A

telomerase

Q

what are the proangiogenic cytokines

A

bFGF

VEGF

Q

tumor marker for:

HCC

A

AFP

Q

tumor marker for:

ovarian

A

CA 125

Q

tumor marker for:

pancreatic

A

CA 19-9

Q

tumor marker for:

melanoma

A

S 100

Q

tumor marker for:

colon

A

CEA

Q

tumor marker for:

astrocytoma

A

S 100

Q

MCC of hypercalcemia

A

primary hyperparathyroidism

Q

what cancers cause hypercalcemia

A

breast

renal

SCC

MM

Q

Mets to bones

A

PTBLK

Q

Mets to brain

A

LBSKG

Q

Mets to liver

A

CSPBL

Q

features of anaplasia

A

inc nucleus-cytoplasmic ratio

prominant nucleus

nuclear chromatin clumping

many mitotic figures

Q

what can inhibit VEGF

A

bevacizumab

Q

MOA of bevacizumab

A

monoclonal Ab vs VEGF

Q

what do cancer cells use to penetrate basement membrane

A

collagenase

hydrolase

Q

what causes cachexia in cancer patients

A

TNF-a

IFN-y

IL 1/6

Q

what tumor causes:

cushings syndrome

A

small cell

Q

what tumor causes:

SIADH

A

small cell

Q

what tumor causes:

hypercalcemia

A

SCC

RCC

MM

breast cancer

Q

what tumor causes:

polycythemia

A

RCC

HCC

pheochromocytoma

hemangioblastoma

Q

what tumor causes:

lambert eaton

A

thymoma

small cell

Q

what tumor causes:

gout

A

leukemia

lymphoma

Q

cancer tumor marker:

bombesin

A

neuroblastoma

lung

gastric

Q

cancer a/w psammoma bodies

A

papillary thyroid

serous cystadenocarcinoma

meningioma

mesothelioma