Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

CK Heme Onc > Heme 1 > Flashcards

Heme 1 Flashcards

1
Q

RLS in:

glycolysis

A

PFK 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

RLS in:

gluconeogenesis

A

F16BP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

RLS in:

TCA

A

isocitrate DH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

RLS in:

glycogen synthesis

A

glycogen synthase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

RLS in:

glycogenolysis

A

glycogen phosphorylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Diabetic drug:

lactic acidosis

A

metformin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Diabetic drug:

SE of hypoglycemia

A

sulfonureas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Diabetic drug:

MOA closes K channels

A

sulfonureas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Diabetic drug:

inhibits a-glucosidase

A

acarbose

miglitol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Diabetic drug:

agonist at PPAR-y

A

TZD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what anticoagulant factors are dependent on vitamin K

A

S

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what coagulant factors are dependent on vitamin K

A

10
9
7
2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

effects of bradykinen

A

vasodilate

inc vascular permeability

inc pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

labs used to monitor:

warfarin

A

PT

INR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

labs used to monitor:

heparin

A

PTT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

labs used to monitor:

enoxaparin

A

factor 10a activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Rx for HIT

A

lapirudin

bivalirudin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what mineral is needed for coagulation

A

Ca

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what can cause a decrease in Ca coagulation

A

citrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

in liver failure, which factor is lost first

A

7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

MOA of acute hemolytic transfusion reaction

A

recurrent meningiococcal infection due to hyperstabalized C3

deficiency on properdin
-would normally cleave C3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

symptoms of clotting factor defect

A

bleeding

hemarthrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

symptoms of platelet defect

24
Q

what stimulates the release of factor 8 and vWF form endothelial cells

A

desmopressin

25
main symptom of hemophilia
hemarthrosis
26
lab changes in hemophilia
inc PTT
27
lab changes in vitamin K def
inc PT and PTT
28
prothrombin gene mutation
G20210A
29
what does AT3 normally activate
``` 7 9 10 11 12 ```
30
heparin given to AT3 def px
reduced inc in PTT
31
MOA of acute hemolytic transfusion reaction
recurrent meningiococcal infection due to hyperstabalized C3 deficiency on properdin -would normally cleave C3
32
symptoms of clotting factor defect
bleeding hemarthrosis
33
symptoms of platelet defect
patechiae
34
what stimulates the release of factor 8 and vWF form endothelial cells
desmopressin
35
main symptom of hemophilia
hemarthrosis
36
lab changes in hemophilia
inc PTT
37
lab changes in vitamin K def
inc PT and PTT
38
prothrombin gene mutation
G20210A
39
what does AT3 normally activate
``` 7 9 10 11 12 ```
40
heparin given to AT3 def px
reduced inc in PTT
41
liver makes all clotting factors except
vWF
42
D-dimers rise from the break down of
fibrin
43
FDP rise from the break down of
fibrin or fibrinogen
44
MOA of enoxaparin
inhibit factor 10a
45
MOA of heparin
increase activation of AT
46
MOA of HIT
heparin binds to platelet factor 4 causing antibody production
47
why are px with HIT hypercoagulable
platelets are dropped but remaining ones are hyperactive
48
MOA of argatroban
directly inhibits thrombin
49
when is lepirudin used
px who take heparin and develops HIT
50
MOA of warfarin
inhibits epoxide reductase -normally recycles vit K no more y-carboxylation of factors
51
what labs change with thrombolytics
inc PT and PTT
52
what is used in atrial fib
warfarin
53
what is used in STEMI
thrombolytics
54
MOA of thrombolytics
increase conversion of plasminogen to plasmin
55
name some thrombolytics
streptokinase urokinase alteplase (tPA) APSAC (anistreplase)
56
how does aminocaproic acid work
inhibits fibrinolysis

CK Heme Onc (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions