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CK Heme Onc > Heme 3 > Flashcards

Heme 3 Flashcards

1
Q

what enzymes are inhibited by lead poisoning

A

ferrochelatase

ALA Hehydratase

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2
Q

antibiotic that:

inhibits peptidyltransferase

A

chloremphenical

streptogramin

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3
Q

antibiotic that:

blocks translocation

A

macrolides

linezolid

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4
Q

antibiotic that:

prevents attachment of tRNA

A

tetracyclines

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5
Q

antibiotic that:

inhibits RNA polymerase

A

rifampin

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6
Q

antibiotic that:

inhibits topoisomerase

A

fluoroquinilones

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7
Q

antibiotic that:

inhibits DHF reductase

A

TMP

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8
Q

test used to diagnose thalassemia

A

hemoglobin electrophoresis

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9
Q

microcytic anemia with difficulty swallowing and glossitis

A

plummer vincent

-iron def

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10
Q

microcytic anemia with greater than 3.5 HbA2

A

B minor

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11
Q

megaloblastic anemia not correctable with B12 or Folate

A

orotic aciduria

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12
Q

megaloblastic anemia with peripheral neuropathy

A

B12 def

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13
Q

microcytic anemia with basophilic stippling

A

lead poisoning

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14
Q

microcytic anemia thats reversible with B12

A

sideroblastic anemia

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15
Q

macrocytic anemia in HIV patient

A

zidovudine

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16
Q

normocytic anemia and red urine in the morning

A

PNA

17
Q

normocytic anemia with elevated creatinine

A

kidney failure

18
Q

what can cause aplastic anemia

A

Virus

drugs

fanconis

19
Q

what is the defect in B thalassemia

A

point mutation in splicing and promoter site

20
Q

what type of cells are seen in B thalassemia

A

target

anistocytes

21
Q

what population is B thalassemia common

A

mediterranean

22
Q

what population is a thalassemia common

A

asian

african

23
Q

Hb seen in 4 deletion in a thalassemia

A

Hb Barts (y4)

24
Q

Hb seen in 3 deletion in a thalassemia

A

HbH (B4)

25
Q

what causes basophilic stippling

A

inhibition of rRNA degradation

26
Q

where are ringed sideroblasts found

A

BM

27
Q

when would you see a crew cut appearance in X ray

A

B thalassemia

Sickle cell

28
Q

how can you differentiate B12 and folate def

A

B12 has neurological symptoms as well as increased methylmalonic acid

29
Q

cells seen in lead poisoning

A

ringed sideroblasts

basophilic stippling

CK Heme Onc (13 decks)

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