Onc 1

Question 1

protozoa a/w:

chagas

Answer 1

t cruzi

Question 2

protozoa a/w:

vaginitis

Answer 2

trichomonas

Question 3

protozoa a/w:

malaria

Answer 3

plasmodium

Question 4

protozoa a/w:

birth defects

Answer 4

toxoplasmsois

Question 5

protozoa a/w:

bloody diarrhea

Answer 5

e histolytica

Question 6

protozoa a/w:

diarrhea, flatulence, bloating

Answer 6

g lamblia

Question 7

how does p53 induce apoptosis

Answer 7

induces transcription of pro-apoptotic genes, such as BAX

Question 8

cancers a/w:

K-RAS

Answer 8

colon

lung

pancreatic

Question 9

cancers a/w:

H-RAS

Answer 9

bladder

kidney

Question 10

cancers a/w:

N-RAS

Answer 10

melanoma

Question 11

cancers a/w:

Rb

Answer 11

Rb

osteosarcoma

Question 12

cancers a/w:

DPC

Answer 12

pancreatic

Question 13

cancers a/w:

APC

Answer 13

FAP

Question 14

cancers a/w:

WT1

Answer 14

wilms

Question 15

cancers a/w:

BRCA

Answer 15

breast

ovarian

Question 16

cancers a/w:

arsenic

Answer 16

lung

skin

hemangiosarcoma

Question 17

cancers a/w:

benzene

Answer 17

leukemia

hodgkins

Question 18

cancers a/w:

beryllium

Answer 18

lung

Question 19

cancers a/w:

cadmium

Answer 19

prostate

lung

Question 20

cancers a/w:

chromium

Answer 20

lung

Question 21

cancers a/w:

nickel sulfate

Answer 21

lung

Question 22

cancers a/w:

radon

Answer 22

lung

Question 23

cancers a/w:

ionizing radiation

Answer 23

AML/CML

thyroid cancer

Question 24

cancers a/w:

UV exposure

Answer 24

SCC

basal cell carcinoma

melanoma

Question 25

what UV type is most problematic

Answer 25

B

causes pyrimidine dimers

Question 26

cancers a/w:

mismatch repair defect

Answer 26

HNPCC

Question 27

cancers a/w:

excision repair defect

Answer 27

XP

Question 28

cancers a/w:

s bovis

Answer 28

colon

Question 29

cancers a/w:

h pylori

Answer 29

gastric

Question 30

cancers a/w:

schistosoma

Answer 30

SCC of the bladder

Question 31

cancers a/w:

c sinensis

Answer 31

biliary carcinoma

Question 32

cancers a/w:

hashimoto

Answer 32

lymphoma

Question 33

cancers a/w:

downs

Answer 33

ALL/AML

Question 34

cancers a/w:

plummer vinson

Answer 34

SCC of the esophagus

Question 35

cancers a/w:

tuberous sclerosis

Answer 35

rabdomyoma

astrocytoma

angiomyolipoma

Question 36

cancers a/w:

ataxia telangiectasia

Answer 36

lymphoma

leukemia

Question 37

cancers a/w:

pagets

Answer 37

osteosarcoma

Question 38

cancers a/w:

nitrosamines

Answer 38

esophageal

stomach

colon

Question 39

cancers a/w:

asbestos

Answer 39

mesothelioma

bronchiogenic carcinoma

Question 40

cancers a/w:

naphthalene

Answer 40

transitional cell bladder cancer

Question 41

cancers a/w:

arsenic

Answer 41

angiosarcoma

SCC of the skin

Question 42

cancers a/w:

EBV

Answer 42

nasopharyngeal

hodgkins

burkitts

Question 43

what is required to phosphorylate Rb

Answer 43

cyclin D binding to CDK4

Question 44

what inhibits CDK4

Answer 44

p53

Question 45

what must happen for tumor suppressor genes to cause cancer

Answer 45

both alleles must be lost

Question 46

what must happen for oncogenes to cause cancer

Answer 46

damage to 1 allele

Question 47

which oncogenes code for tyrosine kinase

Answer 47

ret

erb-B2

abl

Question 48

which oncogenes code for transcription factor

Answer 48

myc’s

c-myc
l-myc
n-myc

Question 49

cancers a/w:

aflatoxin of aspergillous

Answer 49

HCC

Question 50

cancers a/w:

vinyl chloride

Answer 50

angiosarcoma