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CK Heme Onc > Heme 2 > Flashcards

Heme 2 Flashcards

1
Q

how can you diagnose crohns

A

barium shows “string sign”

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2
Q

what allows for RBC to pass through blood vessels

A

spectrin

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3
Q

what bones perform erythropoiesis

A 
sternum
pelvis
ribs
vertebrae
tibia/femur
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4
Q

what is Hb Gower

A

embryonic Hb

Z2 E3

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5
Q

mutation is HbS

A

glu to val

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6
Q

mutation in HbC

A

glu to lys

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7
Q

Hb barts

A

y4

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8
Q

HbH

A

B4

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9
Q

what can cause polycythemia

A 
inc EPO
RCC
HCC
Pheo
hemangioblastoma
chronic hypoxia
downs
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10
Q

RBC pathology a.w:

lead poisoning

A

basophilic stippling

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11
Q

RBC pathology a.w:

G6PD def

A

heinz

bite

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12
Q

RBC pathology a.w:

DIC

A

schistocytes

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13
Q

RBC pathology a.w:

abetalipoproteinemia

A

acanthocyte

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14
Q

RBC pathology a.w:

asplenia

A

howell jolly

target

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15
Q

RLS for heme synthesis

A

ALA synthase

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16
Q

what is anistocytosis

A

varying size

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17
Q

what is poikilocytosis

A

varying shapes

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18
Q

why are reticulocytes bluer than RBC

A

they have more rRNA

19
Q

how do you stain reticulocyte

A

wright giemsa

20
Q

Ab present in A blood type

A

B

21
Q

Ab present in B blood type

A

A

22
Q

Ab present in AB blood type

A

none

23
Q

Ab present in O blood type

A

A

B

24
Q

where would you see:

acanthocyte

A

liver disease

abetalipoproteinemia

25
Q

where would you see:

basophilic stippling

A

TAIL

26
Q

where would you see:

bite cell

A

G6PD

27
Q

where would you see:

ringed sideroblast

A

lead poisoning

28
Q

where would you see:

schistocyte

A

DIC

TTP/HUS

29
Q

where would you see:

tear drop

A

myelofibrosis

30
Q

where would you see:

target

A

HALT

31
Q

what is a heinz body

A

oxidation of iron from ferrous to ferric

denatured Hb precipitates and damages membrane

32
Q

where do you see heinz bodies

A

a thalasemia

G6PD def

33
Q

what are howell jolly bodies

A

basophilic nuclear remnants

34
Q

where do you see howell jolly bodies

A

asplenic px

35
Q

enzyme def in AIP

A

porphobilinogen deaminase

(uroporphyrinogen I synthase

36
Q

enzyme def in PCT

A

uroporphyrinogen decarboxylase

37
Q

enzyme def in lead poisoning

A

ferrochelatase

ALA dehydratase

38
Q

enzyme def in sideroblastic anemia

A

ALA synthase

39
Q

what can inhibit ALA synthase

A

heem and glucose

40
Q

Rx for AIP

A

glucose and heme

41
Q

symptoms of AIP

A

painful abdomen
red wine-colored urine
polyneuropathy

42
Q

symptoms of PCT

A

blistering of cutaneous tissue
hypertrichosis
facial hyperpigmentation

43
Q

symptoms of lead poisoning

A

lead lines

encephalopathy

abdominal colic

drops

44
Q

Rx for lead poisoning

A

dimercaprol and EDTA in adults

succimer for kids

CK Heme Onc (13 decks)

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