Heme 2

Question 1

how can you diagnose crohns

Answer 1

barium shows “string sign”

Question 2

what allows for RBC to pass through blood vessels

Answer 2

spectrin

Question 3

what bones perform erythropoiesis

Answer 3

sternum
pelvis
ribs
vertebrae
tibia/femur

Question 4

what is Hb Gower

Answer 4

embryonic Hb

Z2 E3

Question 5

mutation is HbS

Answer 5

glu to val

Question 6

mutation in HbC

Answer 6

glu to lys

Question 7

Hb barts

Answer 7

y4

Question 8

HbH

Answer 8

B4

Question 9

what can cause polycythemia

Answer 9

inc EPO
RCC
HCC
Pheo
hemangioblastoma
chronic hypoxia
downs

Question 10

RBC pathology a.w:

lead poisoning

Answer 10

basophilic stippling

Question 11

RBC pathology a.w:

G6PD def

Answer 11

heinz

bite

Question 12

RBC pathology a.w:

DIC

Answer 12

schistocytes

Question 13

RBC pathology a.w:

abetalipoproteinemia

Answer 13

acanthocyte

Question 14

RBC pathology a.w:

asplenia

Answer 14

howell jolly

target

Question 15

RLS for heme synthesis

Answer 15

ALA synthase

Question 16

what is anistocytosis

Answer 16

varying size

Question 17

what is poikilocytosis

Answer 17

varying shapes

Question 18

why are reticulocytes bluer than RBC

Answer 18

they have more rRNA

Question 19

how do you stain reticulocyte

Answer 19

wright giemsa

Question 20

Ab present in A blood type

Answer 20

B

Question 21

Ab present in B blood type

Answer 21

A

Question 22

Ab present in AB blood type

Answer 22

none

Question 23

Ab present in O blood type

Answer 23

A

B

Question 24

where would you see:

acanthocyte

Answer 24

liver disease

abetalipoproteinemia

Question 25

where would you see: | basophilic stippling

Answer 25

TAIL

Question 26

where would you see: | bite cell

Answer 26

G6PD

Question 27

where would you see: | ringed sideroblast

Answer 27

lead poisoning

Question 28

where would you see: | schistocyte

Answer 28

DIC TTP/HUS

Question 29

where would you see: | tear drop

Answer 29

myelofibrosis

Question 30

where would you see: | target

Answer 30

HALT

Question 31

what is a heinz body

Answer 31

oxidation of iron from ferrous to ferric denatured Hb precipitates and damages membrane

Question 32

where do you see heinz bodies

Answer 32

a thalasemia G6PD def

Question 33

what are howell jolly bodies

Answer 33

basophilic nuclear remnants

Question 34

where do you see howell jolly bodies

Answer 34

asplenic px

Question 35

enzyme def in AIP

Answer 35

porphobilinogen deaminase (uroporphyrinogen I synthase

Question 36

enzyme def in PCT

Answer 36

uroporphyrinogen decarboxylase

Question 37

enzyme def in lead poisoning

Answer 37

ferrochelatase ALA dehydratase

Question 38

enzyme def in sideroblastic anemia

Answer 38

ALA synthase

Question 39

what can inhibit ALA synthase

Answer 39

heem and glucose

Question 40

Rx for AIP

Answer 40

glucose and heme

Question 41

symptoms of AIP

Answer 41

painful abdomen red wine-colored urine polyneuropathy

Question 42

symptoms of PCT

Answer 42

blistering of cutaneous tissue hypertrichosis facial hyperpigmentation

Question 43

symptoms of lead poisoning

Answer 43

lead lines encephalopathy abdominal colic drops

Question 44

Rx for lead poisoning

Answer 44

dimercaprol and EDTA in adults succimer for kids