Obesity/Metabolic Syndrome Flashcards
What racial group is obesity most prominent in?
Non hispanic black
Hispanic
Non hispanic whites
What racial group is least prominent for obesity?
Asian
Adipose tissue
provides insulation and mechanical support for body
Another name for fat storing cells
adipocytes
What is the healthier tissue to store fat?
peripheral adipose tissue
What is the worse area to store fat?
visceral adipose tissue
Apple shaped
Android
Pear shaped
Gynoid
What fat storage is more common in women?
gynoid
What fat storage is more common in men?
android
What does android fat storage have a higher risk of?
heart disease
HTN
DM
stroke
What is the waist circumference for CAD risk in men?
> 40 in
What is the waist circumference for CAD risk in women?
> 35 in
What is the function of adipokines?
help regulate appetite, food intake, energy expenditure, lipid storage, etc.
Adiponectin
inverse relationship with fat content
protects against atherosclerosis
anti inflammatory effects
*good
Leptin
direct relationship with fat
obese patients become leptin resistant
tells body when it’s had enough to eat = satiety
inhibits fat accumulation
*good
Obesity BMI
BMI >40 kg/m2
If obese, you are at risk for :
DM II, CVD, cancer, HTN, GERD, arthritis, infection and sleep apnea
What are risk factors of obesity?
excess intake vs. output
sedentary lifestyle
low socioeconomic status
cultural aspects of eating
age (40+)
genetics
smoking cessation
secondary disorders
Ghrelin
decreased in obesity
stimulates hunger and controls gastric mobility, acid secretion and stimulates GH
GLP-1
decreases in obesity
reduces appetite
inhibits gastric emptying
increased satiety
Peptide YY
decreased in obesity
reduces appetite
inhibits gastric mobility
increased energy expenditure
Cholecystokinin (CCK)
can decrease in obesity
stimulates gallbladder contraction and release
increased satiety
reduces food intake
slows gastric emptying
Metabolic Syndrome
waist circumference: >40 men, >35 women
triglycerides: >150
HDL: <40 men, <50 women
BP: >130 or >85
fasting glucose: >110