Nystatin

Question 1

therapeutic class

Answer 1

antifungal, superficial type

Question 2

pharmacologic class

Answer 2

polyene

Question 3

pregnancy category

Answer 3

B

Question 4

mechanisms of action

Answer 4

binds to sterols in the fungal cell membrane

allows leakage of intracellular contents across the weakened membrane

Question 5

indications

Answer 5

candida infections of the vagina, skin and mouth
oropharyngeal candidiasis
inflamed subcutaneous lesions
candidiasis of the intestine

Question 6

contraindications

Answer 6

hypersensitivity to the drug

Question 7

precautions

Answer 7

pregnancy and lactation

Question 8

drug interactions

Answer 8

unknown

Question 9

adverse effects

Answer 9

minor skin irritation and burning
contact dermatitis
diarrhea, nausea and vomiting via PO route

Question 10

serious adverse effects

Answer 10

none

Question 11

responsibilites

Answer 11

observe for improvement and report persistent infections

avoid occlusive dressings or ointment on moist dark areas of the body

Question 12

teaching

Answer 12

stop drug, report symptoms of dermatitis
treat oral candidiasis after meals at bedtime
no food or drink while dissolving the troche
remove dentures before rinsing w/ oral suspension, dissolving the troche in the mouth and at night
dust feet, shoes and stockings with nystatin dusting powder