Azoles Flashcards

1
Q

azoles general info

A

largest and most versatile group of antifungals
broad spectrum
can be administered PO and have superior safety profile
both systemic and superficial fungal infections

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2
Q

two chemical classes

A

imidazoles

triazoles

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3
Q

systemic azoles

A

spectrum similar to amphotericin B
less toxic
administered PO

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4
Q

adverse effects

A

nausea & vomiting in 10-20% of patients

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