Nueropathies

Question 1

what are neuropathies

Answer 1

affects PNS

location: axonal or myelin

fiber: motor, sensory, autonomic

pattern: symm, asymm, distal, proximal

Question 2

compare GBS and CMT in terms of how you get it

Answer 2

GBS: acquired

CMT: inherited

Question 3

discuss GBS

Answer 3

progressive symm weakness of limbs c hypo or areflexia

can be s/c sensory prob

unknown cause

Question 4

probable causes of GBS

Answer 4

campylobacter jejuni - GIT

cytomegalovirus - respi

esptein-barr

autoimmune

swine flue vaccine

Question 5

initial clincial manifestations of GBS

Answer 5

starts days-wks p respi or GIT infection

symm limb weakness: proximal –> distal

paresthesia: stocking and glove pattern

DTR: normal then absent

sensory loss and ataxia*

Question 6

advanced clincial manifestations of GBS

Answer 6

CN: facial diplegia, speech probs and papiledema

deep aching pain on back, buttocks and thighs

FATIGUE

autonomic prob and mech vent if severe talaga

Question 7

diagnosis for GBS

Answer 7

CSF: high protein but normal cell count

EMG: demyelination and conduction block

Question 8

discuss CMT

Answer 8

inherited

progressive distal limb wasting and sensory loss

Question 9

diagnosis of CMT

Answer 9

genetic testing and EMG

Question 10

clinical manifestations of CMT

Answer 10

onset in childhood c slow preogression

steppage gait d/t weak peroneals and intrinsic foot muscules
- inverted champagne bottle
- pes cavus
- claw hand

sensory loss in feet