Nucleic Acids Flashcards

1
Q

Nucleic Acids

A

Polymers of nucleotides

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2
Q

Nucleotides

A

Monomers of nucleic acids

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3
Q

Functional groups of: nucleic acids

A
  • phosphate (phosphoric acid)
  • pentose sugar
  • nitrogen-containing base
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4
Q

Polymers of nucleic acids

A
  • DNA

- RNA

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5
Q

DNA

A

Deoxyriboucleic acid

  • pentose sugar doesn’t have O (“deoxy”)
  • stores genetic info
  • 4 nucleotide bases
  • alpha double helix structure (H-bonds)
  • phosphate-sugar-p-s-p poles
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6
Q

DNA nucleotide bases

A
  • A Adenine
  • T Thymine
  • G Guanine
  • C Cytosine
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7
Q

RNA

A

Ribonucleic acid

  • intermediary in the sequencing of amino acids into a protein
  • pentose sugar is ribose
  • structure is single strand with unmatched nucleotides attached
  • 3 classes of RNA
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8
Q

RNA shape

A

Can be straight or shape caused by complimentary nucleotides on the same strand pairing with each other once it’s folded over

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9
Q

RNA nucleotide bases

A
  • A Adenine
  • U Uracil
  • G Guanine
  • C Cytosine
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10
Q

3 Classes of RNA

A
  • mRNA
  • rRNA
  • tRNA
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11
Q

mRNA

A

messenger RNA

-produced by RNA polymerase in the nucleus transcribed from a segment of DNA

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12
Q

rRNA

A

ribosome RNA

  • makes up ribosome (along with proteins)
  • glomps onto mRNA?
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13
Q

tRNA

A

transfer RNA

  • transfers amino acids to ribosomes
  • matches 3 anticodon w/3 codon in the nucleotide pattern of mRNA sequence and moves from A-P-E to make a polypeptide chain (initiates @ P)
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14
Q

Purines

A

Has a double Carbon ring structure

“All Girls are Pure”
-always bonded to a pyrimidine

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15
Q

Pyrimidines

A

Has a single Carbon ring structure

  • U, G, C
  • always bonded to a purine
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16
Q

Complimentary Base Pairing

A

H-bonding between particular N-bases.

DNA: A-T, G-C
RNA: A-U, G-C

17
Q

DNA Replication

A

Synthesis of 2 new & identical DNA double helix strands from 1 ‘parent’ DNA

  • semiconservative
  • 3 steps
18
Q

DNA: Semiconservative

A

DNA replication synthesizes 2 new DNA from the original 1 DNA (used as a template for the ‘daughter’ strands)
-creates something from something, not something from nothing

19
Q

DNA replication

Step 1

A

DNA Helicase unwinds the double helix and unzips it (breaks the H-bonds connecting the complimentary base pairs down the middle of the ladder)

20
Q

DNA replication

Step 2

A

DNA Polymerase uses complimentary base pairing to find the corresponding N-base nucleotides floating around in the nucleus and holds them in place against the parents strands.

21
Q

DNA replication

Step 3

A

DNA Ligase zips and fixes any breaks in the P-S-P-S poles of the 2 new ‘daughter’ helices.

-2 identical strands identical to original DNA molecule

22
Q

ATP

A

Adenosine TriPhosphate

  • another function of the monomer Adenine
  • energy-storing molecule
  • Adenine-Ribose-P-P-P
  • energy stored in the bond between the 2 & 3 Ps
  • released through hydrolysis (ATP -> ADP)