Nucleic acids Flashcards

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1
Q

What is gene expression?

A

DNA—->RNA——>Protein

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2
Q

Types of nucleic acids

A

1)Deoxyribose nucleic acid
2)Ribose nucleic acid

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3
Q

Monomer of nucleic acid is

A

nucleotide

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4
Q

Function of DNA

A

stores genetic information

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5
Q

Nucleotide contains _____ ,______ and ______

A

Pentose sugar
Nitrogen base
Phosphate gp

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6
Q

How polynucleotide are formed?

A

by joining sugar(3’C) to phosphate (5’C) of two nucleotides

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7
Q

Bonds in polynucleotide and is formed by _____ reaction

A

Phosphodiester bond

condensation (removal of water)

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8
Q

Types of nitrogenous base

A

Purine base
1)Adenine
2)Guanine

Pyrimidine base
1)Cytosine
2)Thymine
3)Uracil

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9
Q

When a nucleoside loses phosphate gps,it becomes _____

A

nucleoside(sugar+base)

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10
Q

Structure of pyrimidine

A

one six membered ring

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11
Q

Structure of Purine

A

Six membered ring fused to five membered ring

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12
Q

Which is larger? Purine or pyrimidine?

A

Purine

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13
Q

Which is larger?Purine or pyrimidine?

A

Purine

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14
Q

DNA nucleotide contains

A

1)Deoxyribose sugar
2)Nitrogenous base (A,G,C,T)
3)Phosphate gp

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15
Q

RNA nucleotide contains

A

1)ribose sugar
2)nitrogenous base (A,G,C,U)
3)Phosphate gp

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16
Q

Why DNA strand is called 5’ 3’ strand?

A

b/c phosphodiester bond is formed between phosphate gp of 3’carbon and sugar gp of 5’carbon

17
Q

Phosphate gp is attached to nucleoside by _____ end

A

5’

18
Q

DNA is single or double strand?

A

double strand

19
Q

Two strands of DNA nucleotides are joined by _____ bond between ______

A

hydrogen

nitrogenous base

20
Q

Why DNA strands are called antiparallel?

A

1st strand of DNA is 5’ 3’ and 2nd strand is 3’5’

The nitrogenous base are complementary to each other

21
Q

In DNA,Adenine is joined to ______

A

Thymine (2 hydrogen bond)

22
Q

In DNA,Guanine is joined to ____

A

cytosine (3 hydrogen bond)

23
Q

In DNA helix, ____ are outside and ____ are inside

A

sugar phosphate backbone outside

nitrogenous base inside

24
Q

What is difference b/w sugar of DNA and RNA?

A

DNA-deoxyribose sugar
RNA-ribose sugar

In RNA , OH gp is present in 2nd carbon

25
Q

In RNA,Adenine is joined to ____

A

uracil instead of thymine (2 hydrogen bond)

There is no thymine in RNA

26
Q

In RNA,cytosine is joined to ____

A

guanine (3 hydrogen bond)

27
Q

Types of RNA

A

1)messenger RNA -mRNA
2)ribosomal RNA-rRNA
3)transfer RNA- tRNA

28
Q

All of the RNA are synthesized in ____ & and functions in _____

A

nucleus (rRNA-nucleolus)

cytoplasm

29
Q

In eukaryote,one mRNA is coded for one protein.

True or false?

A

True

30
Q

In prokaryotes,one mRNA is coded for one protein.

True or false?

A

False

one mRNA is coded for different proteins

31
Q

Function of mRNA

A

protein synthesis
(DNA transcribes genetic information into mRNA which is leaves by nuclear pores)

32
Q

Function of rRNA

A

binds with protein to form RIBOSOME

33
Q

Function of tRNA

A

carried genes from codon to ribosome