Non-specific immune defences Flashcards
Keep pathogens outside of body (e.g. skin) Hint: Barriers
Physical Barriers
Name the cells that engulf pathogens and cell debris?
Phagocytes
Carried out by NK cells that destroy abnormal cells?
Immunological surveillance
Chemical messengers that coordinate the defences against viral infections are called what?
Interferons
a system of circulating proteins that assist antibodies in the destruction of pathogens is called what?
Complement
This is localised to the site of damage and limits the spread of infection or injury. What am i?
Inflammatory response
What accelerates tissue metabolism and the activity of defences?
A fever
What cells are responsible for immunological surveillance?
NK cells
Provides a physical barrier/.
Integumentary system
What type of cells are Neutrophils, eosinophils & macrophages
Phagocytes
Phagocyte, found in blood that phagocytosis cellular debris or invading bacteria?
Neutrophil
Phagocyte found in blood phagocytes pathogens that are coated with antibodies?
Eosinophils
Phagocytes that are permanently in specific tissues?
Fixed macrophages
Phagocytes that travel through the body,a arriving at the site of an injury by migrating through adjacent tissues:
Free macrophages
The term when phagocytes leave capillaries by squeezing between adjacent endothelial cells?
Diapedesis
The term where Phagocytes may be attracted to or repelled by chemicals in surrounding fluid?
Chemotaxis
Protein made by NK cells to create pores in target cells are called what?
Perforins
The usual component in plasma membranes of target cells that NK cells recognise?
Tumour specific antigen
The constant monitoring of normal tissues by NK cells
Immunological surveillance
These small proteins are released by activated lymphocytes and macrophages that binds to receptors and via second messengers trigger the production of antiviral proteins?
Interferon’s
These 11 proteins that interact with each other in chain reaction to produce activated forms that target bacterial cell walls and plasma membranes, stimulate inflammation, attract phagocytes or enhance phagocytes?
Complement proteins
Is the erythrocytes a white blood cell?
No
What is the most abundant white blood cell?
Neutrophil