Blood Flashcards

1
Q

What makes up 37 - 54% of total blood volume?

A

Formed elements

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2
Q

What are erythrocytes?

A

Red blood cells

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3
Q

RBC are thin, bi-concave cells. True or False?

A

True

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4
Q

The most abundent cell found in the blood is called what?

A

Red blood cell

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5
Q

What cell binds to oxygen in the lungs and carries it to tissues throughout the body where it is exchanged for the waste product, carbon dioxide?

A

Red blood cell

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6
Q

What is the name of the percentage of whole blood volume contributed by red blood cells?

A

Haematocrit

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7
Q

What are fragments of cells found suspended in plasma?

A

Platelets

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8
Q

What key role do platelets have?

A

blood clotting

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9
Q

What are leukocytes?

A

White blood cells

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10
Q

What is the primary function of white blood cells?

A

defense

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11
Q

There are several types of white blood cells, each with specialized functions?

A

True

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12
Q

What is a clear yellow fluid, comprised mainly of water (91.5%) ?

A

Plasma

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13
Q

The majority of substances found in the blood are what transported within the plasma?

A

Proteins

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14
Q

What are albumins, fibrinogens, globulins and enzymes?

A

Proteins transported within plasma

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15
Q

Nutrients, electrolytes, dissolved gases, organic waste products and hormones can be transported in what?

A

Plasma

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16
Q

What is erythropoiesis?

A

The production of red blood cells

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17
Q

In adults, where are new red blood cells produced?

A

Red bone marrow

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18
Q

Haemocytoblasts are what?

A

Multipotent stem cells that produce red blood cells

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19
Q

These stem cells are derived from multipotent stem cells and differentiate into erthroblasts?

A

Myeloid

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20
Q

What is the earliest distinguishable red blood cell precursor?

A

Proerythroblast

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21
Q

What is the last stage of red blood cell with a nucleus that disintegrates?

A

Erythroblast (normoblast)

22
Q

What contains fragments of the endoplasmic reticulum and is usually found in bone marrow, with a small amount in circulation?

A

Reticulocyte

23
Q

A hormone that is produced in the kidneys which stimulates an increase in red blood cell production and is produced when the body is in a stage of hypoxia, or lack of oxygen?

A

Erythropoietin

24
Q

Red blood cells circulate for how many days?

25
When membranes of RBC begin to disintegrate, damaged cells are removed by what?
Macrophages
26
What happens to iron at the end stage of the RBC life cycle?
Returns to red bone marrow or is stored in the liver
27
What happens to haemoglobin at the end stage of the RBC life cycle? Hint: Haem, globin, bile
``` Haem = converts to bilirubin by macrophages Globin = the protein portion is digested to be used for synthesis of new proteins Bile = is secreted into the small intestine and eliminated through faeces ```
28
Why are RBC bi-concave in shape?
increases surface area to carry more oxygen
29
Do RBC have a nucleus?
No
30
What consists of the protein globin?
Haemoglobin
31
How many oxygen molecules does each haemoglobin bind to?
4 (one bound to each iron)
32
What part of the blood makes it bright red when exposed to oxygen?
Haemoglobin
33
What are the 3 types of Antigens?
A, B or Rh
34
What are the two major blood groups?
ABO group and Rh group
35
Type A blood express what type of antigens?
Type A
36
Type B blood express what type of antigens?
Type B
37
Type AB blood express what type of antigens?
Type A and B
38
Type O blood express what type of antigens?
Neither A or B
39
What are agglutinins?
Antibodies
40
What antibodies are produced in Type A blood?
Anti-B
41
What antibodies are produced in Type B blood?
Anti-A
42
What antibodies are produced in Type AB blood?
No antibodies produced
43
What antibodies are produced in Type O blood?
Both anti-A and anti-B are produced
44
Individuals who display Rh antigen on their RBC membranes are Rh positive or negetive?
Positive
45
Individuals who lack Rh antigen on their RBC membranes are Rh positive or negetive?
Negetive
46
What are the phases of haemostasis?
1. Vascular phase 2. Platelet phase 3. Blood clotting
47
In what phase of haemostasis is there contraction of smooth muscle in the blood vessel wall, constricting the vessel?
Vascular
48
What haemostasis phase immediately slows blood loss and is triggered by neural reflexes and chemicals from activated platelets?
Vascular
49
What does it mean by aggregration of platelets and what phase of haemostasis is it?
The temporary seal is created by platelets, found in platelet phase.
50
What are the stages of the platelet phase?
1. Adhesion 2. Platelet release reaction 3. Aggregation
51
Blood cells trapped within a mesh of protein fibrin threads are what?
Blood clot
52
What are the two pathways that activate clotting?
Intrinsic and extrinsic