Non-narcotic analgesics

Question 1

non-selective NSAID names + MOA

Answer 1

profen, fenac, aspirin, naproxen, indomethacin, ketorolac –> cox 1 + 2 inhibitor

Question 2

selective NSAID names + MOA

Answer 2

coxib –> cox 2 inhibitor

Question 3

NSAID effects

Answer 3

analgesic, antipyretic, anti-inflammatory

Question 4

coxib indications

Answer 4

arthritis, dysmenorrhea, polyposis

Question 5

acetaminophen indications

Answer 5

pregnancy 3rd trimester, GI toxicity, use w/ warfarin/anticoagulants

Question 6

NSAID DDIs

Answer 6

warfarin –> increased INR + bleeding

Question 7

NSAID ADEs

Answer 7

increased bleeding + miscarriage, Reye’s syndrome, TEN > SJS, pregnancy 3rd trimester

Question 8

NSAID contraindications

Answer 8

renal, cardiovascular, elderly, comorbidities

Question 9

aspirin unique characteristics

Answer 9

cardioprotective

Question 10

coxib unique characteristics

Answer 10

less GI effects

Question 11

acetaminophen unique characteristics

Answer 11

no GI + cardiovascular effects

Question 12

acetaminophen MOA

Answer 12

cox 1 + 2 inhibitor

Question 13

partially selective NSAIDS

Answer 13

etodolac, meloxicam

Question 14

cox inhibitor function

Answer 14

inhibit prostaglandins

Question 15

acetaminophen effects

Answer 15

analgesic, antipyretic