GI

Question 1

2 most common causes of PUD

Answer 1

H. pylori (HPI), NSAIDs

Question 2

Bismuth quadruple preferred when? how many times a day?

Answer 2

penicillin allergy, 4x

Question 3

clarithromycin preferred when? how many times a day?

Answer 3

no penicillin allergy (used w/ amoxicillin), 2x (test for resistance)

Question 4

drugs used to get rid of HPI

Answer 4

bismuth quadruple, clarithromycin concomitant

Question 5

prazole, tidine RR

Answer 5

2.5, 2.3

Question 6

H2RAs for PUD equally effective when given

Answer 6

2x daily/1x daily at bedtime

Question 7

H2RAs GERD dosing

Answer 7

2x daily

Question 8

PPI GERD dosing, potency compared to H2RAs

Answer 8

1x daily, more potent

Question 9

tidine MOA

Answer 9

H2RA

Question 10

prazole MOA

Answer 10

PPI

Question 11

setron MOA

Answer 11

5HT3 (serotonin) receptor antagonist

Question 12

pitant MOA

Answer 12

NK receptor antagonist

Question 13

tidine treats but is not indicated for

Answer 13

PUD

Question 14

prazole indications

Answer 14

PUD, GERD

Question 15

setron indications

Answer 15

emesis

Question 16

pitant indications

Answer 16

emesis

Question 17

tidine ADEs

Answer 17

fever, neutropenia, thrombocytopenia, community-acquired pneumonia

Question 18

prazole ADEs

Answer 18

community-acquired pneumonia, osteoporosis + bone fracture, hypomagnesmia, decreased vitamin B12

Question 19

setron ADEs

Answer 19

headache, fatigue, malaise

Question 20

pitant ADEs

Answer 20

fatigue, anorexia, disorientation/dizziness

Question 21

5HT3 receptor antagonists that don’t end in setron

Answer 21

metoclopramideb, promethazinec dronabinol nabilone