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foundations > Chronic hypertension > Flashcards

Chronic hypertension Flashcards

1
Q

B blocker MOA

A

decrease BP by blocking B1+B2 adrenergic receptors (decreased HR + myocardial contractility)

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2
Q

a blocker MOA

A

prevents catecholamine release –> decreased peripheral vasoconstriction (decreased BP)

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3
Q

Intrinsic sympathomimetic activity definition

A

partially stimulate B receptors while blocking catecholamines

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4
Q

cardio-selective definition

A

targets B1 (non-selective at higher doses)

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5
Q

cardio-nonselective definition + names

A

target B1 + B2, propanolol, timolol, nadolol, pindolol

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6
Q

cardio-nonselective + a1 blocker names

A

carvedilol, labetalol

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7
Q

ophthalmic B blocker names + indication

A

levobunolol, betaxolol, metipranolol, carteolol, timolol maleate, levobetaxolol

glaucoma

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8
Q

cardio-selective effect on HR + BP

A

larger effect on HR, lower effect on BP

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9
Q

cardio-nonselective effect on HR + BP

A

lower effect on HR, larger effect on BP

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10
Q

lol, olol, alol, ilol MOA

A

B adrenergic receptor blocker

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11
Q

darone MOA

A

a + B adrenergic receptor blocker

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12
Q

(z)osin MOA

A

a1 receptor blocker

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13
Q

asteride MOA

A

5-a blocker

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14
Q

lol, olol, alol, ilol indications

A

angina pectoris, arrythmias, myocardial infarction, prophylaxis, HF, tremors, hypertension

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15
Q

amiodarone indications

A

ventricular + post-op arrythmias, afib

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16
Q

dronedarone indications

A

paroxysmal/atrial fibrillation

17
Q

(z)osin indications

A

BPH, hypertension

18
Q

asteride indications

A

BPH, alopecia

19
Q

lol, olol, alol, ilol DDIs

A

CYP2D6, p-gp, diabetes meds

20
Q

darone DDIs

A

fluquinolones, warfarin, CYP3A4

21
Q

lol, olol, alol, ilol ADEs

A

bradycardia, hypotension, fatigue, impotence, dizziness, depression, decreased libido

22
Q

darone ADEs

A

fibrosis pneumonitus, hypo/hyper thyroidism, ophthalmic, photosensitivity

23
Q

(z)osin ADEs

A

priapism, orthostatic hypotension, retrograde ejaculation

24
Q

asteride ADEs

A

pregnancy category X, decreased urinary flow

25
Q

dronedarone BBW

A

class III/IV HF, chronic atrial fibrillation

foundations (14 decks)

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