anxiolytics Flashcards
ceiling effect
benzodiazepines better than barbs for resp depression
barb name
barbitol
barb OD
resp depression
barb class
IV (withdrawal, dependence, tolerance)
barb indications
anxiolytic, sedative, hypnotic, antiseizure
meprobamate MOA
binds GABA-A receptor
meprobamate indication
anxiolytic, sedative, myorelaxant
meprobamate class
IV
meprobamate OD
lethal
benzodiazepine names
azopam, azo, azolam, azep
benzo MOA
GABA agonist
benzo indications
anxiolytic, sedative, hypnotic, antiseizure, myorelaxant, AWS
benzo OD
not fatal unless used w other CNS depressants
benzo class
IV
benzo withdrawal
can be fatal
buspirone MOA
serotonin + dopamine agonist
buspirone indications
anxiolytic
buspirone pros
no misuse, tolerance, dependence
buspirone cons
no immediate effect, interacts w CYP3A4