NME 2.31 Flashcards
describe link reaction during high cellular energy?
- PDh kinase will inhibit PDH
- reduce conversion of pyruvate to acetyl CoA
describe link reaction during low cellular energy?
- PDH phosphatase will stimulate PDH
- increase conversion of pyruvate to acetyl CoA
function of kreb cycle?
- provides ATP
- provides reduced NAD and FAD for energy generation
what happens to kreb cycle when there is high cellular energy?
reduce kreb cycle
what happens to kreb cycle when there is low cellular energy?
increase kreb cycle
how many ATP does glycolysis produce?
- 2 ATP
how many ATP does link reaction produce?
zero
how many ATPs does kreb cycle produce?
2 atp
how many ATP does electron transport chain produce?
- 28 ATP
where does electron transport chain occur?
- inner membrane of mitochondria
describe electron transport chain?
- 5 proteins lined up and electrons pass through
- as electron pass through help movement of protons into the intermembrane space
which complex are electrons from NADH moved to?
complex I or NADH dehydrogenase
which complex are electrons from FADH2 moved to?
complex 2 or succinate dehydrogenase
why is complex V important?
produce ATP
what is Coenzyme Q for?
- involved in electrons from complex II and III
what is cytochrome c for?
- involved in moveing electrons from complex III and IV
what is complex IV called?
cytochrome c oxidase
chat is complex V called?
- atp synthase
how does ATP synthase produce ATP?
- as protons moved into intermembrane space
- high concentrationa nd diffuse back in and cause rotation of the ATP synthase and produce ATP
what is the importance of oxygen?
- oxygen is last electron acceptor
- oxygen needed for kreb cycle
- oxygen needed for electron transport chain
- NADH and FADH2 can no longer release electrons without oxygen
what does carbon monoxide and cyanide stop?
- since oxygen is last electron acceptor
- inhibit transfer of electrons from complex IV
what does oligomycin do?
- inhibit ATP synthase
what does dinitrophenol do?
- uncoupling chemical
- cease ATP production
what does uncoupling chemical mean?
- create proton leak
what is complex III called?
cytochrome bc-1
