NME 2.1 Flashcards
what is the anatomical structure of exocrine salivary and pancreas glands?
- secrete by ducts
- external secretion
- exocrine pancreas secretes digestive enzymes into small intestine
what is the anatomical structure of endocrine salivary and pancreas glands?
- no ducts
- secrete directly into blood or surrounding tissue
- internal secretion such as hormones
- pancreas is a mixed endocrine/exocrine organ
what are tubular glands?
- the cell lies along the ducts
examples of simple tubular?
- intestinal glands
- sweat glands
examples of compound tubular?
- gastric glands
what are acinar glands?
- cells in sac at the end of the duct
- acinar is berry like structure
examples simple acinar glands?
- sebaceous
examples compounds acinar glands?
- pancreas
- parotid
what does compound mean?
- branched duct system
what is compound tubuloacinar?
- branched tubules within the acinar
example of compound tubulo-acinar?
- submandibular
what is the difference between tubular and acinus on histology?
- tubular have lighter stain
- acinus have a darker stain
is the pancreas retroperitoneal?
- yes
what is the endocrine function of pancreas?
- secrete hormones from islets of langerhans
- insulin
- glucagon
what is the exocrine function of pancreas?
- pancreatic juice
- digestive enzymes
- alkaline to neutralise gastric acid
where is the uncinate process of the pancreas?
- on the C-shape of the duodenum
- secretion of substances into duodenum
which two tubes joins and from ampulla of vater?
- bile duct
- pancreatic duct
where does ampulla of vater enter the duodenum?
- major duodenal papilla
what controls the major duodenual papilla?
- sphincter of oddi
how is the pancreas organised?
- divided into lobules
- secertory units contain acini
the process of secretion through the branching duct system?
moves from acinus to intercalated duct to interlobular duct to main pancreatic duct
what is surrounded by the exocrine tissue?
islet of langerhans
what do pancreatic acinar cells do?
- there are zymogens granules
- golgi and rER for protein production
what are zymogens granules?
- inactive enzyme precursors
what does centroacinar duct cells do?
modify pancreatic juice
what is the mixture of secretion for submandibular?
- 4:1 serous: mucous
- 70% of total salivary flow
what is the mixture of secretion for parotid?
- 20:1 serous: mucous
- 25% of total salivary flow
what is the mixture of secretion for sublingual?
- 3:7 serous: mucous
- 5% of total salivary flow
what is the salivary gland process of secretion (like which duct secretions have to go through)
- acinus
- intercalated duct
- striated duct
- intralobular duct
- interlobular duct
- lobar duct
- main duct
what is xerostomia?
dryness of mouth
what is excessive sialorrhoea?
excess salivary production
what is sialadenitis?
inflammation of salivary glands
what is sialolithiasis?
there is a stone in the duct of salivary gland normally submandibular duct (wharton’s duct)