nfección por virus de la Parotiditis. Flashcards

1
Q

las primeras celulas infectadas son las de la mucosa nasal

A
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2
Q

PRIMERA REPLICACION: mucosa nasal

A

en los ganglios linfaticos infecta celulas mononucleoras, monocitos

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3
Q

da viremia, paperas o parotiditis meningitis, orquitis, pancreatitis

A

organo blanco principal: glandulas parotidas

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4
Q

periodo de incubacion?

A

16-18 dias

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5
Q

7 dias antes hasta 9 despues aun se transmite

A

perido maximo de transmisibilidad: 2 dias antes y 5 despues de sintomas

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6
Q

necrosis de las celulas infectadas en glandulas salivales

A

viremia 3 a 5 dias

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7
Q

organo mas afectado testiculos

A

aumento mas de lo normal en LCr

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8
Q

FUERTEMENTE NEUROTROPICO

A

COMPLICACION MAS FUERTE fuera DE PAROTITIDITIS ES LA ORQUITIS

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9
Q

PRINCIPALES ORGANOS DEL VIRUS:
1) glandulas salivales
2) SNC
3) pancreas
4) testituclos

A

Síntomas prodrómicos : febricula,
dolor muscular (cuello), cefalea,
malestar general y anorexia.

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10
Q

Dolor, edema y tumefacción de
glándulas parótidas.

A

transmision: goticulas respiratorios

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11
Q

orquitis 30%

A

DIAGNOSTICO DIFERENCIAL:
* infecciones virales: Influenza AH3N2,…
✓ Parotiditis supurada (unilateral)
✓ Parotiditis recurrente: fenotiazina y yoduros.
✓ Calculo salival
✓ Linfadenitis preauricular
✓ Tumores de parotida
✓ Sarcoidosis

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12
Q

DIAGNOSTICO:
Leucopenia con linfocitosis relativa.
✓ Pleocitosis
✓ Amilasemia (amilasa baja)

  • RT.PCR
  • muestras bucales o orina hasta 10 dias
  • cultivos
    *
A

METODO SEROLOGICOS:
 IgM especifica (5, 7dias),
 IgM Vacunados?
 e IgG incremento: Fase aguda y convalescencia, es útil? No predice

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13
Q

EPIDEMIOLOGIA:
- cosmopolita
- diseminacion: saliva, aerosol secreciones, fomites, orina, liquido seminal

A

PREVENCION:
✓ Inmunización activa:
* MMR o triple viral
(parotiditis, sarampión y
rubeola) también por
cepa monovalente Jeryl
Lynn.
* Efec 80% y 88%
✓ Vacunación: ´TV 97-99%;
87-89%
✓ Brotes: 3ª dosis

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14
Q

MUJERES MAYOR COMPLICACION: mastitis

A

SORDERA UNILATERAL EN 4%

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