Neurotrophic DLA Flashcards
1
Q
What is. The impact of neurotrophin family on growth factors
A
Neurotrophins (family of Growth factors) Brain-derived neurotrophic factor (BDNF)
NT3, NT4/5, NT6 : (BDNF-related)
Early in development, neurotrophins appear to be provided by the neurons themselves and by the mesenchymal tissues through which the axons grow.
Later, after their axons reach their targets, sensory neurons begin to express NGF receptors and become dependent on target-derived NGF for survival.
2
Q
What is the effect of NGF on PNS?
A
Parasympathetic & Motor neurons were relatively unaffected
The animals showed poor response to stress,( in treated mice)
